Endoluminal Therapy for Esophageal Disease: An Introduction

Herbert C. Wolfsen

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


This introductory article summarizes decades of research from many dedicated gastrointestinal endoscopists. It provides a background to Barrett esophagus (BE), exploring the risk of progression to dysplasia and esophageal adenocarcinoma. Two premalignant conditions, BE and colon adenoma, are compared, including their progression to esophageal adenocarcinoma and colon and rectal carcinoma, respectively. A comparison of the risks of surgical treatment and post-surgical complications of these cancers and of the strikingly different paradigms for their prevention is presented. The article concludes with the rationale for endoscopic treatment of Barrett disease.

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalGastrointestinal Endoscopy Clinics of North America
Issue number1
StatePublished - Jan 2010


  • Argon plasma coagulation
  • Barrett esophagus
  • Cryotherapy
  • Dysplasia
  • Endoscopic mucosal resection
  • Multipolar electrocoagulation
  • Photodynamic therapy
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Gastroenterology


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