Emerging therapies for refractory angina.

Daniel Satran, Jay H. Traverse, Gregory W. Barsness, Amir Lerman, Robert D. Simari, Anil K. Poulose, Randall K. Johnson, Timothy D. Henry

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


In recent years, improvements in both pharmacologic and revascularization therapies have greatly increased life expectancy for patients with coronary artery disease (CAD). As patients with more extensive CAD live longer, many develop myocardial ischemia and clinical angina that is not amenable to traditional revascularization therapy. Patients with severe, symptomatic, chronic CAD have been described as having refractory angina; they have also been termed "no-option" patients. This article discusses clinical management of this unique and growing group of patients and emerging therapeutic options including pharmacologic agents, enhanced external counterpulsation therapy, therapeutic angiogenesis, neurostimulation, and transmyocardial revascularization.

Original languageEnglish (US)
Pages (from-to)36-39
Number of pages4
JournalMinnesota medicine
Issue number1
StatePublished - Jan 2008

ASJC Scopus subject areas

  • Medicine(all)


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