Effects of vessel curvature on intracranial aneurysmal flow

Y. Hoi, H. Meng, B. R. Bendok, L. R. Guterman, L. N. Hopkins

Research output: Contribution to journalConference articlepeer-review


The effects of parent vessel curvature on the hemodynamic forces for lateral saccular aneurysms are evaluated by using computational fluid dynamics (CFD). As the vessel curvature increases, flow impinges the distal neck and enters the aneurysm violently, causing both the pressure and shear stress at the distal neck to increase. High-pressure and high wall shear stress zones at the distal neck expand with the increasing of vessel curvature. The location of maximal wall shear stress implies that the growth or rupture of aneurysm may initiate in this region. Moreover, the effects of parent vessel curvature on aneurysm hemodynamics may eventually help to predict the risk of individual aneurysm rupture. Implantation of stents has the dual effect of disrupting the flow into the aneurysm and altering the radius of curvature. The study of the effects of vessel curvature effects on flow thus has new implications for stent design and implantation.

Original languageEnglish (US)
Pages (from-to)1337-1338
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
StatePublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002


  • Intracranial aneurysm
  • Stent
  • Vessel curvature
  • Wall shear stress

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics


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