Effect of referral bias on assessing survival in ALS

Eric J. Sorenson, Jayawant Mandrekar, Brian Crum, J. Clarke Stevens

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


We assessed the effect of referral bias on patients with ALS treated at our medical center. A total of 132 subjects were treated by our center over the past 3 years. The referral population had a median survival of 29 months compared to 18 months for the local population (p = 0.007). Referral bias should be addressed when assessing the efficacy of self-selected therapies in the setting of a tertiary ALS clinic.

Original languageEnglish (US)
Pages (from-to)600-602
Number of pages3
Issue number8
StatePublished - Feb 2007

ASJC Scopus subject areas

  • Clinical Neurology


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