Drug-induced parkinsonism

J. A. Van Gerpen

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


BACKGROUND - Drug-induced parkinsonism is common but often unrecognized. In addition to neuroleptics, many medications of diverse chemical nature may induce or exacerbate parkinsonism REVIEW SUMMARY - Reports in the literature of drug-induced parkinsonism or of an underlying parkinsonian disorder exacerbated by a medication were located using MEDLINE, and pertinent bibliographies were reviewed. The range of medications that may induce or exacerbate parkinsonism spans the medical specialties. Along with neuroleptics, selective-serotonin reuptake inhibitors, lithium, valproic acid, calcium channel blockers, antiarrhythmics, procholinergics, chemotherapeutics, amphotericin B, estrogens, and others have been implicated. CONCLUSIONS - This review seeks to enhance clinicians' knowledge of potential medications producing iatrogenic parkinsonism and encourage their vigilance in recognizing it.

Original languageEnglish (US)
Pages (from-to)363-370
Number of pages8
Issue number6
StatePublished - Nov 2002


  • Drug-induced parkinsonism
  • Neuroleptics
  • Parkinson's disease
  • Parkinsonism

ASJC Scopus subject areas

  • Clinical Neurology


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