Diagnostic Approach in Myeloproliferative Neoplasms

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter discusses contemporary diagnosis in myeloproliferative neoplasms (MPNs), which is according to the World Health Organization (WHO) system; this system is primarily based on morphology but also includes information from cytogenetic and molecular studies. The WHO recognizes five major categories of myeloid malignancies; one of these categories is MPNs, which comprise eight subcategories: chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF), systemic mastocytosis (SM), chronic eosinophilic leukemia-not otherwise specified (CEL-NOS), chronic neutrophilic leukemia (CNL), and MPN unclassifiable (MPN-U). Bone marrow morphology is the cornerstone of specific diagnosis in MPNs.

Original languageEnglish (US)
Title of host publicationCancer Consult
Subtitle of host publicationExpertise for Clinical Practice
Number of pages7
ISBN (Electronic)9781118589199
ISBN (Print)9781118589212
StatePublished - Jun 20 2014


  • Bone marrow (BM) mastocytosis
  • Bone marrow morphology
  • Myeloid malignancies
  • Myeloproliferative neoplasms (MPNs)
  • Peripheral blood (PB) cytosis

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Diagnostic Approach in Myeloproliferative Neoplasms'. Together they form a unique fingerprint.

Cite this