@article{69c799f31d29483eab001d26dd426f70,
title = "Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis",
abstract = "Transthyretin amyloidosis is a fatal disorder that is characterized primarily by progressive neuropathy and cardiomyopathy. It occurs in both a mutant form (with autosomal dominant inheritance) and a wild-type form (with predominant cardiac involvement). This article guides clinicians as to when the disease should be suspected, describes the appropriate diagnostic evaluation for those with known or suspected amyloidosis, and reviews the interventions currently available for affected patients.",
keywords = "familial amyloid cardiomyopathy, familial amyloid polyneuropathy, genetics, liver transplantation",
author = "Gertz, {Morie A.} and Benson, {Merrill D.} and Dyck, {Peter J.} and Martha Grogan and Terresa Coelho and Marcia Cruz and Berk, {John L.} and Violaine Plante-Bordeneuve and Schmidt, {Hartmut H.J.} and Giampaolo Merlini",
note = "Funding Information: Dr. Gertz is an advisory board member of and has received honoraria from Isis Pharmaceuticals. Dr. Coelho has received financial support to attend scientific meetings from Isis Pharmaceuticals, Alnylam, and Pfizer; and has received honoraria from Pfizer for educational activities. Dr. Cruz has served as an advisor for Pfizer, Isis Pharmaceuticals, Alnylam Pharmaceuticals, and FoldRx Pharmaceuticals; has received support as a clinical investigator from FoldRx Pharmaceuticals, Isis Pharmaceuticals, and Alnylam Pharmaceuticals; and currently serves on the THAOS (a disease registry capturing natural history and effect of the therapies on TTR amyloidosis) scientific advisory board. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. Publisher Copyright: {\textcopyright} 2015 American College of Cardiology Foundation.",
year = "2015",
doi = "10.1016/j.jacc.2015.09.075",
language = "English (US)",
volume = "66",
pages = "2451--2466",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Elsevier USA",
number = "21",
}