Diagnosis and therapy of biliary tract malignancy

A. Rumalla, B. T. Petersen

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Bile duct and gallbladder cancer are relatively uncommon. Predisposing factors include primary sclerosing cholangitis and gallstones larger than 3 centimeters. Patients present with signs of biliary obstruction and cholestasis. A serum CA 19-9 elevated above 100 U/mL is a useful marker. The diagnosis is implied on imaging studies and confirmed by tissue obtained at endoscopic retrograde cholangiopan-creatography or surgery, or by the clinical course. Surgery is the only curative therapy and survival is improved with resection of early stage disease. Endoscopic or percutaneous transhepatic stenting provides effective palliation. Generally, survival is less than 1 year. Copyright (C) 2000 by W.B. Saunders Company.

Original languageEnglish (US)
Pages (from-to)168-173
Number of pages6
JournalSeminars in Gastrointestinal Disease
Issue number3
StatePublished - 2000

ASJC Scopus subject areas

  • Gastroenterology


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