Designer natriuretic peptides

Candace Y W Lee; Hsiao Lieu; John C Jr. Burnett

doi:10.231/JIM.0b013e3181946fb2

Designer natriuretic peptides

Candace Y W Lee, Hsiao Lieu, John C Jr. Burnett

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that were designed in our laboratory are reviewed, and future directions for research and development of designer NPs are discussed.

Original language	English (US)
Pages (from-to)	18-21
Number of pages	4
Journal	Journal of Investigative Medicine
Volume	57
Issue number	1
DOIs	https://doi.org/10.231/JIM.0b013e3181946fb2
State	Published - Jan 2009

Keywords

Hybrid peptides
Natriuretic peptide
Renal function

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

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10.231/JIM.0b013e3181946fb2

Cite this

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title = "Designer natriuretic peptides",

abstract = "Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that were designed in our laboratory are reviewed, and future directions for research and development of designer NPs are discussed.",

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author = "Lee, {Candace Y W} and Hsiao Lieu and Burnett, {John C Jr.}",

year = "2009",

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KW - Renal function

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Designer natriuretic peptides

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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