Delayed aneurysm regrowth and recanalization after Guglielmi detachable coil treatment. Case report

Robert A. Mericle, Ajay K. Wakhloo, Demetrius K. Lopes, Giuseppe Lanzino, Lee R. Guterman, L. Nelson Hopkins

Research output: Contribution to journalArticlepeer-review

89 Scopus citations


Guglielmi detachable coil (GDC) treatment for complicated cerebral aneurysms is an attractive option that has become widely accepted in recent years. This technique is usually considered only if the patient harbors an aneurysm that is not a good candidate for surgical clipping. However, the definition of 'surgical candidate' varies among institutions, and many patients worldwide are being treated with GDCs as primary therapy. Although most centers currently perform follow-up angiography at 6 months to 1 year, others do not routinely perform it after an initially good result. The authors present a case that indicates longer follow up may be necessary and illustrates some of the pitfalls of GDC treatment. This 56-year-old man presented to the emergency room with a Hunt and Hess Grade II subarachnoid hemorrhage and was found to have a wide-necked basilar apex aneurysm. Because of associated medical comorbidities, it was decided to treat the aneurysm with endovascular techniques. The patient did well on follow-up angiography at 1 year postprocedure. However, at approximately 2 years follow up, the aneurysm was demonstrated to have dramatically recanalized and regrown, requiting open surgical intervention. Endovascular coiling was insufficient to treat this aneurysm and complicated definitive surgical management because a large coil mass had been placed in the operative field. It can be inferred from this case that angiographic follow up of these types of lesions may be beneficial up to 2 years after GDC treatment.

Original languageEnglish (US)
Pages (from-to)142-145
Number of pages4
JournalJournal of neurosurgery
Issue number1
StatePublished - Jul 1998


  • Basilar apex aneurysm
  • Endovascular therapy
  • Guglielmi detachable coils
  • Recanalization
  • Regrowth

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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