Death related to propofol use in an adult patient

Nancy D. Perrier; Yvonne Baerga-Varela; Michael J. Murray

doi:10.1097/00003246-200008000-00066

Death related to propofol use in an adult patient

Nancy D. Perrier, Yvonne Baerga-Varela, Michael J. Murray

Anesthesiology

Research output: Contribution to journal › Article › peer-review

104 Scopus citations

Abstract

Objective: To report an adult trauma patient fatality related to propofol administration. Design: Retrospective case review. Setting: Trauma intensive care unit (ICU) in a level one trauma center. Patient: An 18-yr-old man involved in a motor vehicle crash. Interventions: Treatment for multiple trauma injuries and propofol sedation. Measurements and Main Results: Posttrauma ICU monitoring was performed. The patient developed cardiac arrhythmia, metabolic acidosis, and cardiac failure, which resulted in death. Conclusion: Death related to propofol infusion can occur in adults as well as in pediatric patients.

Original language	English (US)
Pages (from-to)	3071-3074
Number of pages	4
Journal	Critical care medicine
Volume	28
Issue number	8
DOIs	https://doi.org/10.1097/00003246-200008000-00066
State	Published - Jan 1 2000

Keywords

Arrhythmia-bradycardia
Cardiac failure
Complica tions
Death
Hyperlipidemia
Hypotension
Metabolic acidosis
Methemoglobinemia
Propofol
Pulseless electrical activity
Sedative-anesthetics
Trauma

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

Access to Document

10.1097/00003246-200008000-00066

Cite this

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title = "Death related to propofol use in an adult patient",

abstract = "Objective: To report an adult trauma patient fatality related to propofol administration. Design: Retrospective case review. Setting: Trauma intensive care unit (ICU) in a level one trauma center. Patient: An 18-yr-old man involved in a motor vehicle crash. Interventions: Treatment for multiple trauma injuries and propofol sedation. Measurements and Main Results: Posttrauma ICU monitoring was performed. The patient developed cardiac arrhythmia, metabolic acidosis, and cardiac failure, which resulted in death. Conclusion: Death related to propofol infusion can occur in adults as well as in pediatric patients.",

keywords = "Arrhythmia-bradycardia, Cardiac failure, Complica tions, Death, Hyperlipidemia, Hypotension, Metabolic acidosis, Methemoglobinemia, Propofol, Pulseless electrical activity, Sedative-anesthetics, Trauma",

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T1 - Death related to propofol use in an adult patient

AU - Perrier, Nancy D.

AU - Baerga-Varela, Yvonne

AU - Murray, Michael J.

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N2 - Objective: To report an adult trauma patient fatality related to propofol administration. Design: Retrospective case review. Setting: Trauma intensive care unit (ICU) in a level one trauma center. Patient: An 18-yr-old man involved in a motor vehicle crash. Interventions: Treatment for multiple trauma injuries and propofol sedation. Measurements and Main Results: Posttrauma ICU monitoring was performed. The patient developed cardiac arrhythmia, metabolic acidosis, and cardiac failure, which resulted in death. Conclusion: Death related to propofol infusion can occur in adults as well as in pediatric patients.

AB - Objective: To report an adult trauma patient fatality related to propofol administration. Design: Retrospective case review. Setting: Trauma intensive care unit (ICU) in a level one trauma center. Patient: An 18-yr-old man involved in a motor vehicle crash. Interventions: Treatment for multiple trauma injuries and propofol sedation. Measurements and Main Results: Posttrauma ICU monitoring was performed. The patient developed cardiac arrhythmia, metabolic acidosis, and cardiac failure, which resulted in death. Conclusion: Death related to propofol infusion can occur in adults as well as in pediatric patients.

KW - Arrhythmia-bradycardia

KW - Cardiac failure

KW - Complica tions

KW - Death

KW - Hyperlipidemia

KW - Hypotension

KW - Metabolic acidosis

KW - Methemoglobinemia

KW - Propofol

KW - Pulseless electrical activity

KW - Sedative-anesthetics

KW - Trauma

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Death related to propofol use in an adult patient

Abstract

Keywords

ASJC Scopus subject areas

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