Current paradoxes and changing paradigms in vaccinology

Gregory A. Poland

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Other than the provision of clean water, food and sanitation, no other deliberate human intervention has prolonged the human life span as much as the provision of vaccines and the control of infectious diseases. Since 1950, 25 vaccines have been licensed in the US, 15 of these for routine universal use in the population. On the horizon are vaccines not only to prevent infectious diseases, but also vaccines against cancer and a host of other human ills. Despite these public health and scientific accomplishments however, the manner in which we think about, develop and apply vaccines to the public health has common heuristic flaws which prevent realizing the full benefits of vaccines to society. This paper will discuss a number of current paradoxes and changing paradigms related to the field of vaccinology.

Original languageEnglish (US)
Pages (from-to)1605-1611
Number of pages7
Issue number13-14
StatePublished - Jan 1999


  • Paradigms
  • Paradoxes
  • Vaccines

ASJC Scopus subject areas

  • Molecular Medicine
  • General Immunology and Microbiology
  • General Veterinary
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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