Cryoballoon ablation in Chinese patients with paroxysmal atrial fibrillation: 1-year follow-up

Tian You Ling, Qi Jin, Wen Qi Pan, Ning Zhang, Chang Jian Lin, Hon Chi Lee, Li Qun Wu

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Objectives: We assessed the effectiveness and safety of cryoballoon ablation (CBA) in the Chinese population with paroxysmal atrial fibrillation (AF) with a 1-year follow-up and determined the association of early recurrence of atrial tachyarrhythmias (ERAT) with late recurrence (LR). Methods: A total of 114 patients (age 61 ± 10 years, 78 males) with paroxysmal AF who underwent CBA were consecutively enrolled. After procedures, patients were observed for 3 days with continuous electrocardiogram monitoring in the hospital with routine follow-up visits at 3 months, 6 months, and 1 year. Documented atrial tachyarrhythmia >30 seconds was defined as recurrence. ERAT was defined as any recurrence during the first 3 months, and LR was recurrence between 3 and 12 months. Results: With the first 3 months as blanking period, 76% of patients were free of LR at 12 months. Five patients (4%) experienced complications, including phrenic nerve palsy, stroke, and groin complications. Forty-five percent of patients had ERAT in the first 3 months and 31% of patients had ERAT in the first 3 days. Patients with ERAT had higher LR rate (LRR) than those without ERAT (43% vs 8%, P < 0.001). The LRR of patients with ERAT only in the first 3 days was lower than those with ERAT both in the first 3 days and in 4–90 days (29% vs 64%, P = 0.036). Conclusions: CBA was an effective and safe treatment option for paroxysmal AF. Patients with ERAT had higher LRR after CBA of AF. The time when ERAT occurred had an impact on LRR.

Original languageEnglish (US)
Pages (from-to)1067-1072
Number of pages6
JournalPACE - Pacing and Clinical Electrophysiology
Issue number10
StatePublished - Oct 2017


  • atrial fibrillation
  • blanking period
  • cryoballoon ablation
  • pulmonary vein isolation
  • recurrence

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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