Crohn's disease of the ileoanal pouch

Amy L. Lightner, John H. Pemberton, Edward J. Loftus

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations


Crohn's disease (CD) of the pouch is an increasingly recognized diagnosis after ileal pouch-anal anastomosis. This post-ileal pouch-anal anastomosis diagnosis in conjunction with pouchitis remains the leading reason for pouch excision. Unfortunately, CD of the pouch remains a difficult diagnosis with lack of a uniform definition largely because of its similarity to common postoperative pouch complications, including pouchitis, abscess formation, or stricture at the anastomosis. Once diagnosed, treatment algorithms largely include multimodal therapy including biologics. This review focuses on the definition, etiology, diagnosis, and treatment for CD of the pouch, a postoperative de novo diagnosis of CD.

Original languageEnglish (US)
Pages (from-to)1502-1508
Number of pages7
JournalInflammatory bowel diseases
Issue number6
StatePublished - Jun 1 2016


  • CD of the pouch
  • Crohn's disease
  • IPAA
  • pouchitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Gastroenterology


Dive into the research topics of 'Crohn's disease of the ileoanal pouch'. Together they form a unique fingerprint.

Cite this