TY - JOUR
T1 - Coronary Disease in Pregnancy
T2 - Myocardial Infarction and Spontaneous Coronary Artery Dissection
AU - Campbell, Katherine H.
AU - Tweet, Marysia S.
N1 - Funding Information:
M.S.T. is supported by the Office of Research on Women s Health s Building Interdisciplinary Careers in Women s Health (BIRCWH) Program at the National Institutes of Health (HD65987). K.H.C. declares that there is nothing to disclose.
Funding Information:
Correspondence: Marysia S. Tweet, MD, Department of Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN. E-mail: tweet. marysia@mayo.edu M.S.T. is supported by the Office of Research on Women’s Health’s Building Interdisciplinary Careers in Women’s Health (BIRCWH) Program at the National Institutes of Health (HD65987). K.H.C. declares that there is nothing to disclose.
Publisher Copyright:
© 2020Wolters Kluwer Health, Inc. All rights reserved.
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Pregnancy-related maternal mortality and morbidity rates continue to increase in the United States despite global improvements in maternal outcomes. The unique hemodynamic and physiological changes of pregnancy results in a 3-to 4-fold increased risk of acute myocardial infarction (AMI) which causes a substantial proportion of all maternal cardiac deaths. In addition to atherosclerosis, pregnancy-associated AMI is commonly caused by nonatherosclerotic etiologies such as spontaneous coronary artery dissection, embolus to the coronary artery, and coronary vasospasm. Herein, the epidemiology, etiologies, presentation, diagnosis, and management of AMI in pregnancy is discussed along with future directions for multidisciplinary care.
AB - Pregnancy-related maternal mortality and morbidity rates continue to increase in the United States despite global improvements in maternal outcomes. The unique hemodynamic and physiological changes of pregnancy results in a 3-to 4-fold increased risk of acute myocardial infarction (AMI) which causes a substantial proportion of all maternal cardiac deaths. In addition to atherosclerosis, pregnancy-associated AMI is commonly caused by nonatherosclerotic etiologies such as spontaneous coronary artery dissection, embolus to the coronary artery, and coronary vasospasm. Herein, the epidemiology, etiologies, presentation, diagnosis, and management of AMI in pregnancy is discussed along with future directions for multidisciplinary care.
KW - acute myocardial infarction
KW - postpartum
KW - pregnancy
KW - spontaneous coronary artery dissection
KW - sudden cardiac arrest
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U2 - 10.1097/GRF.0000000000000558
DO - 10.1097/GRF.0000000000000558
M3 - Article
C2 - 32701519
AN - SCOPUS:85090307872
SN - 0009-9201
VL - 63
SP - 852
EP - 867
JO - Clinical Obstetrics and Gynecology
JF - Clinical Obstetrics and Gynecology
IS - 4
ER -