Computed tomography of fatal hepatic rupture due to peliosis hepatis

Ralph L. Smathers, Jay P. Heiken, Joseph K. Joseph, Gary A. Press, Dennis M. Balfe

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Hepatic rupture with subcapsular hematoma and hemoperitoneum is shown by CT in a patient with peliosis hepatis. Peliosis hepatis is pathologically characterized by blood-filled cystic spaces in the liver associated with the administration of anabolic androgenic steroids or oral contraceptive agents, particularly those with large components of estrogen. We report a fatal case in a patient receiving diethylstilbestrol for 3 years. In patients receiving these medications, peliosis hepatis should be considered in the differential diagnosis of low attenuation areas in the liver by CT. These patients are subject to increased risk of spontaneous hepatic rupture.

Original languageEnglish (US)
Pages (from-to)768-769
Number of pages2
JournalJournal of computer assisted tomography
Issue number4
StatePublished - Aug 1984


  • Complications and sequelae
  • Computed tomography
  • Liver
  • Rupture
  • Steroids

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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