Complex sleep apnea associated with use of nasal expiratory positive airway (nEPAP) device

Amit Chopra, Piyush Das, Kannan Ramar, Bruce Staats, Erik K. St Louis

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Complex sleep apnea syndrome (CompSAS) is characterized by predominant obstructive sleep disordered breathing with evolution of central disordered breathing following exposure to nasal continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) patients. We report a case of CompSAS associated with use of a nasal expiratory positive airway (nEPAP, Provent) device. We therefore recommend obtaining objective sleep data to confirm treatment effectiveness of the nEPAP device for OSA prior to long-term prescription. Further research is warranted to understand the underlying pathophysiological mechanisms and risk factors associated with CompSAS.

Original languageEnglish (US)
Pages (from-to)577-579
Number of pages3
JournalJournal of Clinical Sleep Medicine
Issue number5
StatePublished - 2014


  • Complex sleep apnea syndrome
  • Nasal expiratory positive airway
  • Obstructive sleep apnea

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Neurology
  • Clinical Neurology


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