Comparison of the impact of wireless versus catheter-based pH-metry on daily activities and study-related symptoms

Angela G. Bradley, Michael D. Crowell, John K. Dibaise, Hack J. Kim, George E. Burdick, David E. Fleischer, Virender K. Sharma

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


AIMS: To evaluate the variation in tolerance to wireless pH-metry compared with catheter-based pH-metry, and to determine clinical characteristics that might predict reduced tolerance to wireless pH-metry. Methods: Consecutive outpatients (n=341) completing wireless (n=234) or catheter-based pH-metry (n=106) were evaluated. All patients completed the pH-Metry Impact Scale and the pH-Metry Symptoms Scale to assess the impact of the pH-metry on activities of daily living and pH-metry associated changes in study-related symptoms. All data are presented as mean (SD) or odds ratios (95% confidence interval). Results: The impact of pH-metry on activities of daily living were modest, but wireless pH-metry had less impact than catheter-based pH-metry (P=0.01). A sense of foreign body in the chest, chest discomfort, and chest pain were reported more frequently during wireless pH-metry. Difficulty swallowing and painful swallowing were more common during catheter-based pH-metry. Noncardiac chest pain was associated with increased symptom severity. Patients with poor tolerance were twice as likely to have a diagnosis of noncardiac chest pain (odds ratio=2. 53; 95% confidence interval, 1.4-4.6). Conclusions: Wireless pH-metry has less of an impact on activities of daily living but is not associated with fewer study-related symptoms compared with catheter-based pH-metry. The prevalence of specific study-related symptoms does differ between the 2 groups and noncardiac chest pain seems to be the primary risk factor for more severe study-related symptoms and reduced tolerance for wireless pH-metry. This information may be useful in helping to decide which patients should undergo the wireless pH-metry or receive additional counseling on procedural expectations.

Original languageEnglish (US)
Pages (from-to)100-106
Number of pages7
JournalJournal of clinical gastroenterology
Issue number2
StatePublished - Feb 2011


  • dysphagia
  • esophagus
  • gastroesophageal reflux
  • noncardiac chest pain
  • pH-metry
  • wireless pH

ASJC Scopus subject areas

  • Gastroenterology


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