Common Vascular Toxicities of Cancer Therapies

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1 Scopus citations


The introduction of targeted agents into modern cancer therapy pursued the goal of molecularly more specific, and thereby more effective and safer, therapies. Paradoxically, however, several toxicities were brought to greater attention, among these not only cardiac but also vascular toxicities. The latter reach far beyond venous thromboembolism and include a broad spectrum of presentations based on the vascular territories and pathomechanisms involved, including abnormal vascular reactivity, acute thrombosis, or accelerated atherosclerosis. This article provides an overview of the most common presentations and their management strategies.

Original languageEnglish (US)
Pages (from-to)365-384
Number of pages20
JournalCardiology clinics
Issue number4
StatePublished - Nov 2019


  • Atherosclerosis
  • Cancer
  • Myocardial infarction
  • Peripheral arterial disease
  • Stroke
  • Thrombosis
  • Vasospasm

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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