Combined intraocular and systemic rituximab for ocular lymphoproliferative disorder with extranodal marginal zone lymphoma–type morphology after heart transplant

Bashar M. Bata; Jose S Pulido; Sanjay V. Patel; Shakila P. Khan; Diva Salomao; Thomas G. Boyce; Erick D. Bothun

doi:10.1016/j.jaapos.2017.10.016

Combined intraocular and systemic rituximab for ocular lymphoproliferative disorder with extranodal marginal zone lymphoma–type morphology after heart transplant

Bashar M. Bata, Jose S Pulido, Sanjay V. Patel, Shakila P. Khan, Diva Salomao, Thomas G. Boyce, Erick D. Bothun

Ophthalmology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Post-transplant lymphoproliferative disorder (PTLD) has rarely been associated with ocular manifestations. We report a case of bilateral ocular involvement by PTLD with histopathologic features of extranodal marginal zone (MALT) lymphoma in an 8-year-old boy following orthotopic heart transplantation. The anterior segment disease was treated successfully using a combination of intraocular and systemic injections of humanized anti-CD20 antibody (rituximab).

Original language	English (US)
Pages (from-to)	159-161
Number of pages	3
Journal	Journal of AAPOS
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/j.jaapos.2017.10.016
State	Published - Apr 1 2018

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Ophthalmology

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title = "Combined intraocular and systemic rituximab for ocular lymphoproliferative disorder with extranodal marginal zone lymphoma–type morphology after heart transplant",

abstract = "Post-transplant lymphoproliferative disorder (PTLD) has rarely been associated with ocular manifestations. We report a case of bilateral ocular involvement by PTLD with histopathologic features of extranodal marginal zone (MALT) lymphoma in an 8-year-old boy following orthotopic heart transplantation. The anterior segment disease was treated successfully using a combination of intraocular and systemic injections of humanized anti-CD20 antibody (rituximab).",

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T1 - Combined intraocular and systemic rituximab for ocular lymphoproliferative disorder with extranodal marginal zone lymphoma–type morphology after heart transplant

AU - Bata, Bashar M.

AU - Pulido, Jose S

AU - Patel, Sanjay V.

AU - Khan, Shakila P.

AU - Salomao, Diva

AU - Boyce, Thomas G.

AU - Bothun, Erick D.

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Post-transplant lymphoproliferative disorder (PTLD) has rarely been associated with ocular manifestations. We report a case of bilateral ocular involvement by PTLD with histopathologic features of extranodal marginal zone (MALT) lymphoma in an 8-year-old boy following orthotopic heart transplantation. The anterior segment disease was treated successfully using a combination of intraocular and systemic injections of humanized anti-CD20 antibody (rituximab).

AB - Post-transplant lymphoproliferative disorder (PTLD) has rarely been associated with ocular manifestations. We report a case of bilateral ocular involvement by PTLD with histopathologic features of extranodal marginal zone (MALT) lymphoma in an 8-year-old boy following orthotopic heart transplantation. The anterior segment disease was treated successfully using a combination of intraocular and systemic injections of humanized anti-CD20 antibody (rituximab).

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ER -

Combined intraocular and systemic rituximab for ocular lymphoproliferative disorder with extranodal marginal zone lymphoma–type morphology after heart transplant

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