Chronic Daily Headache: A Rational-Approach to a Challenging Problem

Jonathan Gladstone, Eric Eross, David Dodick

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


Chronic daily headache (CDH) is a significant public health problem with 3 to 5% of the population worldwide experiencing daily or near-daily headaches. Patients with CDH can be particularly challenging, and clinicians require a systematic approach to help guide investigations and management. The revised 2004 International Headache Society Classification Criteria introduces formalized criteria for several CDH disorders including chronic migraine and medication overuse headache as well as new daily persistent headache, hemicrania continua, hypnic headache, and SUNCT syndrome. Medication overuse is common in patients with CDH who present to physicians. Familiarity and comfort with drug-withdrawal and detoxification strategies is therefore essential. Patients with chronic migraine and chronic cluster experience significant disability and diminished quality of life. The ability to manage these patients effectively is a rewarding clinical experience.

Original languageEnglish (US)
Pages (from-to)265-275
Number of pages11
JournalSeminars in Neurology
Issue number3
StatePublished - Sep 2003


  • Chronic daily headache
  • Cluster headache
  • Medication overuse headache
  • Migraine

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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