Characterization of reperfused infarcted myocardium from high-frequency intracardiac ultrasound imaging using homodyned K distribution

Xiaohui Hao, Charles J. Bruce, Cristina Pislaru, James F. Greenleaf

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Myocardial changes caused by infarction/reperfusion (contraction band necrosis, hemorrhage, edema, etc.) may result in an increased scatterer density and a variation in scatterer arrangement. This paper, for the first time, models most of the scattering conditions resulting from the interaction of ultrasound and normal/reperfused infarcted myocardium using the homodyned K distribution. Furthermore, this method is used to characterize the change in scatterer density by calculating the effective scatterer number per resolution cell. The reliability and the effects of attenuation and scan conversion on effective scatterer number estimation are discussed. We used in vivo data acquired using high-frequency intracardiac ultrasound imaging (8.5 MHz) from the left and right ventricles of opne-chest pigs in an acute infarction/reperfusion model. The results show that the homodyned K distribution describes the statistical distribution of backscattered signal from both normal and abnormal myocardium. A significant increase in scatterer density occurs in the infarcted region after reperfusion compared with the same region at baseline (normal myocardium prior to occlusion). The scatterer density of the normal region does not change significantly after reperfusion. We conclude that the homodyned K distribution may characterize normal and reperfused infarcted myocardium using high-frequency intracardiac ultrasound images.

Original languageEnglish (US)
Pages (from-to)1530-1542
Number of pages13
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Issue number11
StatePublished - Nov 1 2002

ASJC Scopus subject areas

  • Instrumentation
  • Acoustics and Ultrasonics
  • Electrical and Electronic Engineering


Dive into the research topics of 'Characterization of reperfused infarcted myocardium from high-frequency intracardiac ultrasound imaging using homodyned K distribution'. Together they form a unique fingerprint.

Cite this