Celiac Disease and Non-celiac Gluten Sensitivity

Amanda K. Cartee; Joseph A. Murray

doi:10.1007/978-3-030-01117-8_17

Celiac Disease and Non-celiac Gluten Sensitivity

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Patients with celiac disease and non-celiac gluten sensitivity have similar symptoms which improve on a gluten-free diet. However, what we know about each condition differs greatly. In celiac disease, gluten triggers immune-mediated intestinal inflammation. Serum tissue transglutaminase antibodies and duodenal biopsies are the principal diagnostic tests. Micronutrient deficiencies and consequences such as anemia and bone disease are common. The only treatment is a lifelong gluten-free diet. In contrast, there are no known diagnostic tests for or complications of non-celiac gluten sensitivity. Patients often start a gluten-free diet on their own, making the celiac disease diagnosis more challenging.

Original language	English (US)
Title of host publication	Essential Medical Disorders of the Stomach and Small Intestine
Subtitle of host publication	A Clinical Casebook
Publisher	Springer International Publishing
Pages	353-374
Number of pages	22
ISBN (Electronic)	9783030011178
ISBN (Print)	9783030011161
DOIs	https://doi.org/10.1007/978-3-030-01117-8_17
State	Published - Jan 1 2019

Keywords

Abdominal pain
Celiac disease
Deamidated gliadin
Diarrhea
Gluten challenge
Gluten-free diet
Non-celiac gluten sensitivity
Tissue transglutaminase

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1007/978-3-030-01117-8_17

Cite this

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abstract = "Patients with celiac disease and non-celiac gluten sensitivity have similar symptoms which improve on a gluten-free diet. However, what we know about each condition differs greatly. In celiac disease, gluten triggers immune-mediated intestinal inflammation. Serum tissue transglutaminase antibodies and duodenal biopsies are the principal diagnostic tests. Micronutrient deficiencies and consequences such as anemia and bone disease are common. The only treatment is a lifelong gluten-free diet. In contrast, there are no known diagnostic tests for or complications of non-celiac gluten sensitivity. Patients often start a gluten-free diet on their own, making the celiac disease diagnosis more challenging.",

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Celiac Disease and Non-celiac Gluten Sensitivity

Abstract

Keywords

ASJC Scopus subject areas

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