Case report and literature review of chlorine gas toxicity

Stephen J. Traub, Robert S. Hoffman, Lewis S. Nelson

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Chlorine gas exposure is uncommon in children and when it occurs usually results in mild ocular, oropharyngeal, or respiratory symptoms. Occasionally, however, chlorine gas poisoning may cause severe pulmonary toxicity. We report the case of a 14-y-old boywith a history of asthma who was exposed to chlorine gas as a result of an ill-advised science experiment. His clinical condition deteriorated over the course of several hours, and he required intubation and ventilatory support. During his hospitalization, he developed the acute respiratory distress syndrome. He was treated with positive pressure ventilation, beta-adrenergic agonists, and corticosteroids. After 19 d, he was extubated and subsequently made an excellent recovery. We discuss his case and review the etiology, pathophysiology, clinical presentation, laboratory findings, treatment and possible long-term sequelae of chlorine gas toxicity.

Original languageEnglish (US)
Pages (from-to)235-239
Number of pages5
JournalVeterinary and Human Toxicology
Issue number4
StatePublished - Jan 1 2002

ASJC Scopus subject areas

  • Toxicology
  • veterinary(all)
  • Health, Toxicology and Mutagenesis


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