Brain-responsive neurostimulation in adult-onset rasmussen's encephalitis

Anteneh M. Feyissa; Alaa S. Mohamed; William O. Tatum; Alana S. Campbell; A. Sebastian Lopez-Chiriboga

doi:10.1016/j.ebr.2021.100445

Brain-responsive neurostimulation in adult-onset rasmussen's encephalitis

Anteneh M. Feyissa
, Alaa S. Mohamed
, William O. Tatum
, Alana S. Campbell
, A. Sebastian Lopez-Chiriboga

Neurology

Research output: Contribution to journal › Article › peer-review

Abstract

Epilepsy associated with Rasmussen's encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating consequences on adult patients. Here we present the outcome of a 32-year-old woman with adult-onset Rasmussen's, who was treated with brain-responsive neurostimulation (RNS) after failure of several immunotherapeutic and anti-seizure medications.

Original language	English (US)
Article number	100445
Journal	Epilepsy and Behavior Case Reports
Volume	15
DOIs	https://doi.org/10.1016/j.ebr.2021.100445
State	Published - Jan 2021

Keywords

RNS
Rasmussen's encephalitis
Responsive neurostimulation
drug-resistant epilepsy

ASJC Scopus subject areas

Neurology
Clinical Neurology
Behavioral Neuroscience

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10.1016/j.ebr.2021.100445

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title = "Brain-responsive neurostimulation in adult-onset rasmussen's encephalitis",

abstract = "Epilepsy associated with Rasmussen's encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating consequences on adult patients. Here we present the outcome of a 32-year-old woman with adult-onset Rasmussen's, who was treated with brain-responsive neurostimulation (RNS) after failure of several immunotherapeutic and anti-seizure medications.",

keywords = "RNS, Rasmussen's encephalitis, Responsive neurostimulation, drug-resistant epilepsy",

author = "Feyissa, \{Anteneh M.\} and Mohamed, \{Alaa S.\} and Tatum, \{William O.\} and Campbell, \{Alana S.\} and Lopez-Chiriboga, \{A. Sebastian\}",

note = "Publisher Copyright: {\textcopyright} 2021",

year = "2021",

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doi = "10.1016/j.ebr.2021.100445",

language = "English (US)",

volume = "15",

journal = "Epilepsy and Behavior Case Reports",

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AU - Feyissa, Anteneh M.

AU - Mohamed, Alaa S.

AU - Tatum, William O.

AU - Campbell, Alana S.

AU - Lopez-Chiriboga, A. Sebastian

PY - 2021/1

Y1 - 2021/1

N2 - Epilepsy associated with Rasmussen's encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating consequences on adult patients. Here we present the outcome of a 32-year-old woman with adult-onset Rasmussen's, who was treated with brain-responsive neurostimulation (RNS) after failure of several immunotherapeutic and anti-seizure medications.

AB - Epilepsy associated with Rasmussen's encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating consequences on adult patients. Here we present the outcome of a 32-year-old woman with adult-onset Rasmussen's, who was treated with brain-responsive neurostimulation (RNS) after failure of several immunotherapeutic and anti-seizure medications.

KW - RNS

KW - Rasmussen's encephalitis

KW - Responsive neurostimulation

KW - drug-resistant epilepsy

UR - https://www.scopus.com/pages/publications/85103773464

UR - https://www.scopus.com/pages/publications/85103773464#tab=citedBy

U2 - 10.1016/j.ebr.2021.100445

DO - 10.1016/j.ebr.2021.100445

M3 - Article

AN - SCOPUS:85103773464

SN - 2213-3232

VL - 15

JO - Epilepsy and Behavior Case Reports

JF - Epilepsy and Behavior Case Reports

M1 - 100445

ER -

Brain-responsive neurostimulation in adult-onset rasmussen's encephalitis

Abstract

Keywords

ASJC Scopus subject areas

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