@inproceedings{81566ec08cf44799bf091c48abd58095,
title = "BmQGen: Biomedical query generator for knowledge discovery",
abstract = "A large number of structured and unstructured data (e.g., EHRs, ontologies, reports) have been introduced by the biomedical community. Cross-domain data integration is identified as an important research problem for translational research. From an application perspective, identifying related concepts among medical ontologies is an important goal of life science research. It is essential to analyze how relations are specified to connect concepts in a single ontology or across multiple ontologies. With the explosion of cross domain datasets, it is extremely hard for researchers to discover knowledge from current infrastructures of ontologies. It is mainly a lack of the connectivity between the ontologies' cross domains and ontologies to unstructured data; even if they have specific biomedical knowledge in a more general and comprehensive level. Therefore, there is a need for a mechanism to do semantic partition and query generation for cross domain biomedical knowledge discovery. In this paper, we present such a model that clusters integrated data based on semantic closeness of predicates into different groups and produces meaningful queries to fully discover knowledge over a set of interlinked data sources. We have implemented a prototype of the BmQGen system and evaluated the proposed query model based on the predicate oriented clustering with colorectal surgical cohort from the Mayo Clinic.",
keywords = "biomedical cross domain, knowledge discovery, query generation, semantic",
author = "Feichen Shen and Hongfang Liu and Sunghwan Sohn and Larson, {David W.} and Yugyung Lee",
note = "Publisher Copyright: {\textcopyright} 2015 IEEE.; IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015 ; Conference date: 09-11-2015 Through 12-11-2015",
year = "2015",
month = dec,
day = "16",
doi = "10.1109/BIBM.2015.7359833",
language = "English (US)",
series = "Proceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "1092--1097",
editor = "Schapranow, {lng. Matthieu} and Jiayu Zhou and Hu, {Xiaohua Tony} and Bin Ma and Sanguthevar Rajasekaran and Satoru Miyano and Illhoi Yoo and Brian Pierce and Amarda Shehu and Gombar, {Vijay K.} and Brian Chen and Vinay Pai and Jun Huan",
booktitle = "Proceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015",
}