TY - JOUR
T1 - BiPAP in acute respiratory failure due to myasthenic crisis may prevent intubation
AU - Rabinstein, Alejandro
AU - Wijdicks, Eelco F.M.
PY - 2002/11/26
Y1 - 2002/11/26
N2 - Noninvasive mechanical ventilation using bilevel positive pressure ventilation (BiPAP) has not been studied in acute respiratory failure caused by MG. Eleven episodes in nine patients were initially managed with BiPAP, and endotracheal intubation was avoided in seven of these trials. Presence of hypercapnia (PaCO2 greater than 50 mm Hg) at onset predicted BiPAP failure and subsequent intubation. Results of this preliminary study suggest that a trial of BiPAP may prevent intubation in patients with myasthenic crisis without overt hypercapnia.
AB - Noninvasive mechanical ventilation using bilevel positive pressure ventilation (BiPAP) has not been studied in acute respiratory failure caused by MG. Eleven episodes in nine patients were initially managed with BiPAP, and endotracheal intubation was avoided in seven of these trials. Presence of hypercapnia (PaCO2 greater than 50 mm Hg) at onset predicted BiPAP failure and subsequent intubation. Results of this preliminary study suggest that a trial of BiPAP may prevent intubation in patients with myasthenic crisis without overt hypercapnia.
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U2 - 10.1212/01.WNL.0000033797.79530.16
DO - 10.1212/01.WNL.0000033797.79530.16
M3 - Article
C2 - 12451217
AN - SCOPUS:0037180469
SN - 0028-3878
VL - 59
SP - 1647
EP - 1649
JO - Neurology
JF - Neurology
IS - 10
ER -