Abstract
Current treatment options for Graves hyperthyroidism and the related ophthalmopathy (GO) are not uniformly effective and carry with them potentially serious side effects. As a result, efforts have been focused on the development of novel therapies. Progress has been made, particularly in the production of thyroid-stimulating hormone receptor (TSHR) antagonists, as either monoclonal blocking antibodies or small-molecule ligands. In addition, rituximab (RTX) is the first targeted biological therapy to be studied as treatment for these conditions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 577-579 |
| Number of pages | 3 |
| Journal | Clinical pharmacology and therapeutics |
| Volume | 91 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2012 |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)