Atypical hyperplasia of the breast: Clinical cases and management strategies

Suneela Vegunta; Dawn M. Mussallem; Aparna S. Kaur; Sandhya Pruthi; Christine L. Klassen

doi:10.3949/ccjm.90a.22098

Atypical hyperplasia of the breast: Clinical cases and management strategies

Suneela Vegunta, Dawn M. Mussallem, Aparna S. Kaur, Sandhya Pruthi, Christine L. Klassen

General Internal Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atyp-ical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.

Original language	English (US)
Pages (from-to)	423-431
Number of pages	9
Journal	Cleveland Clinic journal of medicine
Volume	90
Issue number	7
DOIs	https://doi.org/10.3949/ccjm.90a.22098
State	Published - 2023

Keywords

For patients with atypical ductal hyperplasia identified on core needle biopsy
owing to significant risk of finding an associated in situ or invasive malignant lesion
surgical consultation is recom-mended to discuss if surgical excision is warranted based on radiology and pathology concordance

ASJC Scopus subject areas

General Medicine

Access to Document

10.3949/ccjm.90a.22098

Cite this

@article{80d4557ccd044a46be0c8914315e2e56,

title = "Atypical hyperplasia of the breast: Clinical cases and management strategies",

abstract = "Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atyp-ical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.",

keywords = "For patients with atypical ductal hyperplasia identified on core needle biopsy, owing to significant risk of finding an associated in situ or invasive malignant lesion, surgical consultation is recom-mended to discuss if surgical excision is warranted based on radiology and pathology concordance",

author = "Suneela Vegunta and Mussallem, {Dawn M.} and Kaur, {Aparna S.} and Sandhya Pruthi and Klassen, {Christine L.}",

year = "2023",

doi = "10.3949/ccjm.90a.22098",

language = "English (US)",

volume = "90",

pages = "423--431",

journal = "Cleveland Clinic journal of medicine",

issn = "0891-1150",

publisher = "Cleveland Clinic Educational Foundation",

number = "7",

}

TY - JOUR

T1 - Atypical hyperplasia of the breast

T2 - Clinical cases and management strategies

AU - Vegunta, Suneela

AU - Mussallem, Dawn M.

AU - Kaur, Aparna S.

AU - Pruthi, Sandhya

AU - Klassen, Christine L.

PY - 2023

Y1 - 2023

N2 - Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atyp-ical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.

AB - Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atyp-ical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.

KW - For patients with atypical ductal hyperplasia identified on core needle biopsy

KW - owing to significant risk of finding an associated in situ or invasive malignant lesion

KW - surgical consultation is recom-mended to discuss if surgical excision is warranted based on radiology and pathology concordance

UR - http://www.scopus.com/inward/record.url?scp=85163940868&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85163940868&partnerID=8YFLogxK

U2 - 10.3949/ccjm.90a.22098

DO - 10.3949/ccjm.90a.22098

M3 - Review article

C2 - 37400158

AN - SCOPUS:85163940868

SN - 0891-1150

VL - 90

SP - 423

EP - 431

JO - Cleveland Clinic journal of medicine

JF - Cleveland Clinic journal of medicine

IS - 7

ER -

Atypical hyperplasia of the breast: Clinical cases and management strategies

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this