Artificial Intelligence and Machine Learning in Arrhythmias and Cardiac Electrophysiology

Albert K. Feeny, Mina K. Chung, Anant Madabhushi, Zachi I. Attia, Maja Cikes, Marjan Firouznia, Paul A. Friedman, Matthew M. Kalscheur, Suraj Kapa, Sanjiv M. Narayan, Peter A. Noseworthy, Rod S. Passman, Marco V. Perez, Nicholas S. Peters, Jonathan P. Piccini, Khaldoun G. Tarakji, Suma A. Thomas, Natalia A. Trayanova, Mintu P. Turakhia, Paul J. Wang

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Artificial intelligence (AI) and machine learning (ML) in medicine are currently areas of intense exploration, showing potential to automate human tasks and even perform tasks beyond human capabilities. Literacy and understanding of AI/ML methods are becoming increasingly important to researchers and clinicians. The first objective of this review is to provide the novice reader with literacy of AI/ML methods and provide a foundation for how one might conduct an ML study. We provide a technical overview of some of the most commonly used terms, techniques, and challenges in AI/ML studies, with reference to recent studies in cardiac electrophysiology to illustrate key points. The second objective of this review is to use examples from recent literature to discuss how AI and ML are changing clinical practice and research in cardiac electrophysiology, with emphasis on disease detection and diagnosis, prediction of patient outcomes, and novel characterization of disease. The final objective is to highlight important considerations and challenges for appropriate validation, adoption, and deployment of AI technologies into clinical practice.

Original languageEnglish (US)
Pages (from-to)E007952
JournalCirculation: Arrhythmia and Electrophysiology
Issue number8
StatePublished - Aug 1 2020


  • artificial intelligence
  • atrial fibrillation
  • cardiac electrophysiology
  • computers
  • diagnosis
  • machine learning

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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