Appropriateness of the treatment of fatigued patients with stage IV cancer

Andrea L. Cheville, Tiffany Shen, Megan Chang, Jeffrey R. Basford

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Background: Fatigue among patients with cancer is prevalent, disabling, and treatable. While fatigue management guidelines have been in place for a decade, their use remains unclear. Methods: We surveyed 160 patients with stage IV lung (40), breast (40), colon (40), and prostate (40) cancer who reported moderate to severe fatigue (i.e., >5 of 10 on an 11-point numerical rating scale). Participants were queried about receipt of treatments in fatigue management domains emphasized in the National Comprehensive Cancer Network guidelines: general management strategies, activity enhancement, psychosocial strategies, and pharmaceuticals. Results: The cohort was half male, had a mean age of 67, and reported an average fatigue rating of 6.4. Participants reported treatment or receipt of specific guidance in the fatigue management domains as follows: general management strategies 16.8 %, activity enhancement 11.9 %, psychosocial strategies 9.9 %, and pharmaceuticals 37.3 %. Fatigue >7 of 10 increased the likelihood of instruction in activity enhancement but no other domain. Conclusion: The low rates of guideline-congruent treatment reported here are concerning, particularly as better validated behavioral treatments were the least prescribed.

Original languageEnglish (US)
Pages (from-to)229-233
Number of pages5
JournalSupportive Care in Cancer
Issue number1
StatePublished - Jan 2013


  • Cancer
  • Fatigue
  • National Comprehensive Cancer Network

ASJC Scopus subject areas

  • Oncology


Dive into the research topics of 'Appropriateness of the treatment of fatigued patients with stage IV cancer'. Together they form a unique fingerprint.

Cite this