Approach to patients with heart failure and normal ejection fraction

Ahmad A. Elesber, Margaret M. Redfield

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Approximately 50% of patients with a firm clinical diagnosis of heart failure (HF) have a normal ejection fraction. Some patients have valvular disease, but most have underlying diastolic dysfunction that leads to pulmonary and systemic congestion and signs and symptoms of HF. Although diastolic HF is clinically and radiographically indistinguishable from HF with depressed left systolic ventricular function, knowledge of which patients are at risk of diastolic HF, the common clinical profiles, and the common echocardiographic findings enhances the clinician's ability to diagnose diastolic HF with confidence. The prognostic implications of a diagnosis of diastolic HF and the therapeutic approach to such patients are reviewed.

Original languageEnglish (US)
Article number62490
Pages (from-to)1047-1052
Number of pages6
JournalMayo Clinic proceedings
Issue number10
StatePublished - Oct 2001


  • ACE = angiotensin-converting enzyme
  • EF = ejection fraction
  • HF = heart failure

ASJC Scopus subject areas

  • Medicine(all)


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