Antidepressant-Induced Female Sexual Dysfunction

Tierney Lorenz, Jordan Rullo, Stephanie Faubion

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


Because 1 in 6 women in the United States takes antidepressants and a substantial proportion of patients report some disturbance of sexual function while taking these medications, it is a near certainty that the practicing clinician will need to know how to assess and manage antidepressant-related female sexual dysfunction. Adverse sexual effects can be complex because there are several potentially overlapping etiologies, including sexual dysfunction associated with the underlying mood disorder. As such, careful assessment of sexual function at the premedication visit followed by monitoring at subsequent visits is critical. Treatment of adverse sexual effects can be pharmacological (dose reduction, drug discontinuation or switching, augmentation, or using medications with lower adverse effect profiles), behavioral (exercising before sexual activity, scheduling sexual activity, vibratory stimulation, psychotherapy), complementary and integrative (acupuncture, nutraceuticals), or some combination of these modalities.

Original languageEnglish (US)
Pages (from-to)1280-1286
Number of pages7
JournalMayo Clinic proceedings
Issue number9
StatePublished - Sep 1 2016

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Antidepressant-Induced Female Sexual Dysfunction'. Together they form a unique fingerprint.

Cite this