Alzheimer's Disease and Mild Cognitive Impairment

Brendan J. Kelley, Ronald C. Petersen

Research output: Contribution to journalReview articlepeer-review

166 Scopus citations


As our society ages, age-related diseases assume increasing prominence as both personal and public health concerns. Disorders of cognition are particularly important in both regards, and Alzheimer's disease is by far the most common cause of dementia of aging. In 2000, the prevalence of Alzheimer's disease in the United States was estimated to be 4.5 million individuals, and this number has been projected to increase to 14 million by 2050. Although not an inevitable consequence of aging, these numbers speak to the dramatic scope of its impact. This article focuses on Alzheimer's disease and the milder degrees of cognitive impairment that may precede the clinical diagnosis of probable Alzheimer's disease, such as mild cognitive impairment.

Original languageEnglish (US)
Pages (from-to)577-609
Number of pages33
JournalNeurologic clinics
Issue number3
StatePublished - Aug 2007

ASJC Scopus subject areas

  • Clinical Neurology


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