Abstract
Clark and Slevin studied six patients with colorectal cancer who had fluorouracil-induced stomatitis. They observed a decrease in stomatitis in all six patients after treatment with allopurinol mouthwash 1 mg/mL. Two patients with taste abnormalities showed reductions in taste dysfunction. We undertook a similar study to determine whether allopurinol mouthwash can selectively protect the oral mucosa from toxicity. The results were compared with those for a historical control group.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 655-658 |
| Number of pages | 4 |
| Journal | Clinical Pharmacy |
| Volume | 8 |
| Issue number | 9 |
| State | Published - Jan 1 1989 |
ASJC Scopus subject areas
- Pharmaceutical Science