Advances in Nanotechnology-Based Drug Delivery Platforms and Novel Drug Delivery Systems

Krishna Suri; Joy Wolfram; Haifa Shen; Mauro Ferrari

doi:10.1016/B978-0-12-416603-5.00003-1

Advances in Nanotechnology-Based Drug Delivery Platforms and Novel Drug Delivery Systems

Krishna Suri, Joy Wolfram, Haifa Shen, Mauro Ferrari

Research output: Chapter in Book/Report/Conference proceeding › Chapter

7 Scopus citations

Abstract

The human body has a multitude of physiological barriers that must be overcome for systemic delivery of a drug to a target region. Because these barriers are each of a different nature, a multifaceted approach to drug delivery should prove advantageous. Nanotechnology enables the design of multifunctional delivery vehicles that can penetrate biological obstacles. To date, four major design strategies have been utilized to obtain preferential accumulation of nanoparticles: (1) biophysical targeting, (2) molecular targeting, (3) use of biomaterials, and (4) use of external energy. Furthermore, the emergence of next-generation nanoparticles that incorporate nanomaterials that can be activated in a time-sequential manner offers promising tools for medical applications.

Original language	English (US)
Title of host publication	Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies
Publisher	Elsevier Inc.
Pages	41-58
Number of pages	18
ISBN (Electronic)	9780124166615
ISBN (Print)	9780124166035
DOIs	https://doi.org/10.1016/B978-0-12-416603-5.00003-1
State	Published - Jan 5 2015

Keywords

Biological barriers
Drug delivery
Nanomedicine
Nanotechnology
Nanotherapeutics

ASJC Scopus subject areas

Medicine(all)
Immunology and Microbiology(all)

Access to Document

10.1016/B978-0-12-416603-5.00003-1

Cite this

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abstract = "The human body has a multitude of physiological barriers that must be overcome for systemic delivery of a drug to a target region. Because these barriers are each of a different nature, a multifaceted approach to drug delivery should prove advantageous. Nanotechnology enables the design of multifunctional delivery vehicles that can penetrate biological obstacles. To date, four major design strategies have been utilized to obtain preferential accumulation of nanoparticles: (1) biophysical targeting, (2) molecular targeting, (3) use of biomaterials, and (4) use of external energy. Furthermore, the emergence of next-generation nanoparticles that incorporate nanomaterials that can be activated in a time-sequential manner offers promising tools for medical applications.",

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AU - Wolfram, Joy

AU - Shen, Haifa

AU - Ferrari, Mauro

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AB - The human body has a multitude of physiological barriers that must be overcome for systemic delivery of a drug to a target region. Because these barriers are each of a different nature, a multifaceted approach to drug delivery should prove advantageous. Nanotechnology enables the design of multifunctional delivery vehicles that can penetrate biological obstacles. To date, four major design strategies have been utilized to obtain preferential accumulation of nanoparticles: (1) biophysical targeting, (2) molecular targeting, (3) use of biomaterials, and (4) use of external energy. Furthermore, the emergence of next-generation nanoparticles that incorporate nanomaterials that can be activated in a time-sequential manner offers promising tools for medical applications.

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KW - Drug delivery

KW - Nanomedicine

KW - Nanotechnology

KW - Nanotherapeutics

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PB - Elsevier Inc.

ER -

Advances in Nanotechnology-Based Drug Delivery Platforms and Novel Drug Delivery Systems

Abstract

Keywords

ASJC Scopus subject areas

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