A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma

B. T. Welch, P. W. Eiken, T. D. Atwell, T. Peikert, E. S. Yi, F. Nichols, G. D. Schmit

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: Mesothelioma has been considered a difficult pathologic diagnosis to achieve via image-guided core needle biopsy. The purpose of this study was to assess the diagnostic sensitivity of percutaneous image-guided biopsy for diagnosis of pleural mesothelioma. Materials and Methods: Retrospective review was performed to identify patients with a confirmed diagnosis of pleural mesothelioma and who underwent image-guided needle biopsy between January 1, 2002, and January 1, 2016. Thirty-two patients with pleural mesothelioma were identified and included for analysis in 33 image-guided biopsy procedures. Patient, procedural, and pathologic characteristics were recorded. Complications were characterized via standardized nomenclature [Common Terminology for Clinically Adverse Events (CTCAE)]. Results: Percutaneous image-guided biopsy was associated with an overall sensitivity of 81%. No CTCAE clinically significant complications were observed. No image-guided procedures were complicated by pneumothorax or necessitated chest tube placement. No patients had tumor seeding of the biopsy tract. Conclusion: Percutaneous image-guided biopsy can achieve high sensitivity for pathologic diagnosis of pleural mesothelioma with a low procedural complication rate, potentially obviating need for surgical biopsy.

Original languageEnglish (US)
Pages (from-to)860-863
Number of pages4
JournalCardiovascular and Interventional Radiology
Issue number6
StatePublished - Jun 1 2017


  • Mesothelioma
  • Percutaneous image guided biopsy
  • Thoracic intervention

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'A Single-Institution Experience in Percutaneous Image-Guided Biopsy of Malignant Pleural Mesothelioma'. Together they form a unique fingerprint.

Cite this