A novel cytotoxic lignan from Seseli annuum L.

Ivan Vučković, Vladimir Trajković, Slobodan Macura, Vele Tešević, Peda Janaćković, Slobodan Milosavljević

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


A new tetrahydrofuranoid lignan named seselinone was isolated from the aerial parts of Seseli annuum, together with three known lignans (eudesmin, magnone A and hemone) and prenylated coumarin umbelliprenin. Seselinone and eudesmin showed cytotoxic activity against C6 rat glioma cell cultures.

Original languageEnglish (US)
Pages (from-to)790-792
Number of pages3
JournalPhytotherapy Research
Issue number8
StatePublished - Aug 2007


  • Cytotoxicity
  • Eudesmin
  • Lignans
  • Seseli annuum
  • Seselinone

ASJC Scopus subject areas

  • Pharmacology


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