@article{6ed5334d19c948af8be2149a764ce040,
title = "A new thermode perfusion system for local temperature manipulation",
abstract = "A thermode perfusion system incorporating a miniature heater was used to alter the local temperature in the brain of the marmot and of the cat. In the marmot, local temperature has been changed or clamped over a range of 35-39°C at the rate of 0.4°C/W. In the cat, local temperature has been increased by 1.5°C and decreased by 2°C at the rate of 0.15°C/W.",
keywords = "Local temperature, Manipulation, Marmot, Thermode perfusion system",
author = "Mills, {S. H.} and South, {F. E.} and Miller, {V. M.}",
note = "Funding Information: The miniature heater was incorporated into a perfusion system which is detachable from the chronically implanted thermode as illustrated in Fig. 1. This system permits the subject animal maximum freedom of movement while several temperature and sleep state parameters are monitored. Appropriate perfusant temperature is maintained by altering the electrical power to the miniature heater. Flow within the perfusion system was more stable after a rigid concentric adaptor (Fig. 1) was inserted where the parallel lines joined the thermode. This adaptor consists of a 24 gauge stainless steel tube inserted through and welded to a length of stainless steel 18 gauge tubing. When attachment to the head of the animal was made, the stem of the 1 Supported, in part, by NSF Grant GB-42761 and by the Dalton Research Center. 2Current Address: Dr. S. H. Mills, Department of Biology, Central Missouri State University, Warrensburg, MO 64093 3Current Address and send reprint requests to: Dr. Frank E. South, Director, School of Life and Health Sciences, University of Delaware, Newark, DA 19711 4Current Address: Dr. Virginia M. Miller, Department of Psychology, University of Virginia, Charlottesville, VA 22901",
year = "1977",
month = apr,
doi = "10.1016/0031-9384(77)90072-5",
language = "English (US)",
volume = "18",
pages = "725--727",
journal = "Physiology and Behavior",
issn = "0031-9384",
publisher = "Elsevier Inc.",
number = "4",
}