A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues

Keyphrases

• Multiple mutations 100%
• Deterministic Model 100%
• Closed Solution 40%
• Whole Genome Sequencing 20%
• Cell Senescence 20%
• Cell Division 20%
• Clonal Diversity 20%
• Tissue Structure 20%
• Mutation Profiling 20%
• Single-cell Clone 20%
• Clonal Population 20%
• Telomere Shortening 20%
• Childhood Acute Lymphoblastic Leukemia 20%
• Single-point mutation 20%
• Multi-compartment 20%
• Hierarchical Tissues 20%
• Biological Constraints 20%
• Clonal Dynamics 20%
• Reproductive Capacity 20%

Biochemistry, Genetics and Molecular Biology

• Dynamics 100%
• Solution and Solubility 66%
• Cell Division 33%
• Tissue Structure 33%
• Whole Genome Sequencing 33%
• Telomere Shortening 33%
• Clonal Population 33%

Immunology and Microbiology

• Dynamics 100%
• Solution and Solubility 66%
• Whole Genome Sequencing 33%
• Cell Division 33%
• Telomere Shortening 33%
• Tissue Structure 33%