A case of IgG4-associated cholangitis and autoimmune pancreatitis responsive to corticosteroids

Aaron J. Smal, Conor G. Loftus, Thomas C. Smyrk, Todd H. Baron

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Background: A 72-year-old male presented to the emergency department with epigastric pain, anorexia and progressive jaundice of 1 week's duration. He had no prior history of gastrointestinal illness, diabetes or cancer. He did not smoke or consume alcohol. He did have a family history of colon and bone cancer. Investigations: Biochemical and serologic studies, CT scan, abdominal ultrasound, endoscopic ultrasound, endoscopic retrograde cholangiopancreatography, biliary cytology, pancreas needle biopsies and immunohistochemical stainings. Diagnosis: Autoimmune pancreatitis with IgG4-associated sclerosing cholangitis affecting the extrahepatic biliary ducts and mimicking primary sclerosing cholangitis and cholangiocarcinoma. Management: Corticosteroids and immunomodulatory therapy.

Original languageEnglish (US)
Pages (from-to)707-712
Number of pages6
JournalNature Clinical Practice Gastroenterology and Hepatology
Issue number12
StatePublished - 2008

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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