A 64-year-Old patient assigned male at birth with COPD and worsening dyspnea while on estrogen and antiandrogen agents

Gustavo A. Cortes-Puentes; Caroline J. Davidge-Pitts; Cesar A. Gonzalez; Megan M. Dulohery Scrodin; Cassie C. Kennedy; Kaiser G. Lim

doi:10.1016/j.rmcr.2023.101876

A 64-year-Old patient assigned male at birth with COPD and worsening dyspnea while on estrogen and antiandrogen agents

Gustavo A. Cortes-Puentes, Caroline J. Davidge-Pitts, Cesar A. Gonzalez, Megan M. Dulohery Scrodin, Cassie C. Kennedy, Kaiser G. Lim

Pulmonary and Critical Care Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Among patients with COPD, ventilatory inefficiency in response to exercise can be due to respiratory muscle dysfunction or expiratory flow limitation causing air-trapping and dynamic hyperinflation. We discuss a case of severe ventilatory limitation in response to exercise due to reduced respiratory muscle mass in the setting of gender-affirming hormone therapy (GAHT), and how the interpretation of pulmonary function testing (PFT) and respiratory symptoms among transgender and gender diverse (TGD) patients can be influenced by GAHT.

Original language	English (US)
Article number	101876
Journal	Respiratory Medicine Case Reports
Volume	44
DOIs	https://doi.org/10.1016/j.rmcr.2023.101876
State	Published - Jan 2023

Keywords

COPD
Chronic obstructive pulmonary disease
Gender affirming care
LVRS
Lung volume reduction surgery
PFT
Personalized medicine
Pulmonary function testing
Pulmonary mechanics
Transgender

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

Access to Document

10.1016/j.rmcr.2023.101876

Cite this

@article{9726329a1bbb4f55954aae7a07798200,

title = "A 64-year-Old patient assigned male at birth with COPD and worsening dyspnea while on estrogen and antiandrogen agents",

abstract = "Among patients with COPD, ventilatory inefficiency in response to exercise can be due to respiratory muscle dysfunction or expiratory flow limitation causing air-trapping and dynamic hyperinflation. We discuss a case of severe ventilatory limitation in response to exercise due to reduced respiratory muscle mass in the setting of gender-affirming hormone therapy (GAHT), and how the interpretation of pulmonary function testing (PFT) and respiratory symptoms among transgender and gender diverse (TGD) patients can be influenced by GAHT.",

keywords = "COPD, Chronic obstructive pulmonary disease, Gender affirming care, LVRS, Lung volume reduction surgery, PFT, Personalized medicine, Pulmonary function testing, Pulmonary mechanics, Transgender",

author = "Cortes-Puentes, {Gustavo A.} and Davidge-Pitts, {Caroline J.} and Gonzalez, {Cesar A.} and {Dulohery Scrodin}, {Megan M.} and Kennedy, {Cassie C.} and Lim, {Kaiser G.}",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

month = jan,

doi = "10.1016/j.rmcr.2023.101876",

language = "English (US)",

volume = "44",

journal = "Respiratory Medicine Case Reports",

issn = "2213-0071",

publisher = "W.B. Saunders Ltd",

}

TY - JOUR

T1 - A 64-year-Old patient assigned male at birth with COPD and worsening dyspnea while on estrogen and antiandrogen agents

AU - Cortes-Puentes, Gustavo A.

AU - Davidge-Pitts, Caroline J.

AU - Gonzalez, Cesar A.

AU - Dulohery Scrodin, Megan M.

AU - Kennedy, Cassie C.

AU - Lim, Kaiser G.

PY - 2023/1

Y1 - 2023/1

N2 - Among patients with COPD, ventilatory inefficiency in response to exercise can be due to respiratory muscle dysfunction or expiratory flow limitation causing air-trapping and dynamic hyperinflation. We discuss a case of severe ventilatory limitation in response to exercise due to reduced respiratory muscle mass in the setting of gender-affirming hormone therapy (GAHT), and how the interpretation of pulmonary function testing (PFT) and respiratory symptoms among transgender and gender diverse (TGD) patients can be influenced by GAHT.

AB - Among patients with COPD, ventilatory inefficiency in response to exercise can be due to respiratory muscle dysfunction or expiratory flow limitation causing air-trapping and dynamic hyperinflation. We discuss a case of severe ventilatory limitation in response to exercise due to reduced respiratory muscle mass in the setting of gender-affirming hormone therapy (GAHT), and how the interpretation of pulmonary function testing (PFT) and respiratory symptoms among transgender and gender diverse (TGD) patients can be influenced by GAHT.

KW - COPD

KW - Chronic obstructive pulmonary disease

KW - Gender affirming care

KW - LVRS

KW - Lung volume reduction surgery

KW - PFT

KW - Personalized medicine

KW - Pulmonary function testing

KW - Pulmonary mechanics

KW - Transgender

UR - http://www.scopus.com/inward/record.url?scp=85160560718&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85160560718&partnerID=8YFLogxK

U2 - 10.1016/j.rmcr.2023.101876

DO - 10.1016/j.rmcr.2023.101876

M3 - Article

AN - SCOPUS:85160560718

SN - 2213-0071

VL - 44

JO - Respiratory Medicine Case Reports

JF - Respiratory Medicine Case Reports

M1 - 101876

ER -

A 64-year-Old patient assigned male at birth with COPD and worsening dyspnea while on estrogen and antiandrogen agents

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this