2D phosphorene nanosheets, quantum dots, nanoribbons: Synthesis and biomedical applications

Xifeng Liu, Bipin Gaihre, Matthew N. George, Yong Li, Maryam Tilton, Michael J. Yaszemski, Lichun Lu

Research output: Contribution to journalReview articlepeer-review


Phosphorene, also known as black phosphorus (BP), is a two-dimensional (2D) material that has gained significant attention in several areas of current research. Its unique properties such as outstanding surface activity, an adjustable bandgap width, favorable on/off current ratios, infrared-light responsiveness, good biocompatibility, and fast biodegradation differentiate this material from other two-dimensional materials. The application of BP in the biomedical field has been rapidly emerging over the past few years. This article aimed to provide a comprehensive review of the recent progress on the unique properties and extensive medical applications for BP in bone, nerve, skin, kidney, cancer, and biosensing related treatment. The details of applications of BP in these fields were summarized and discussed.

Original languageEnglish (US)
Pages (from-to)2768-2803
Number of pages36
JournalBiomaterials Science
Issue number8
StatePublished - Apr 21 2021

ASJC Scopus subject areas

  • Biomedical Engineering
  • Materials Science(all)


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