We observed immunostaining for the 1,25-dihydroxyvitamin D3 receptor (VDR) and calbindin-D(28k) in neurons, but not glial cells, of fetal rat dorsal root ganglia (DRG) from days 13 through 21 of gestation. Dispersed cultures of DRG collected from rat fetuses at gestational day 15 also contained epitopes for VDR and calbindin-D(28k) in neurons, but not in glial cells. 1,25-Dihydroxyvitamin D3, through VDR, may perform significant functions in the development of neuronal cells.
- 1,25-Dihydroxyvitamin D receptor
- Dorsal root ganglia
ASJC Scopus subject areas
- Developmental Neuroscience
- Developmental Biology