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Keyphrases
CD28 Signaling
100%
CD28
100%
T Cell Activation
88%
T Cell Receptor
77%
ERK5
66%
MEK5
55%
Gene-deficient Mice
55%
Specific Aims
44%
Overexpression
44%
Interleukin-2
33%
MEKK2
33%
MEKK3
33%
Biochemical Approaches
22%
Adaptor
22%
Autoimmune Disease
22%
T Cells
22%
Jurkat T Cells
22%
Phosphorylation
22%
Regulatory Role
11%
Mitogen-activated Protein Kinase
11%
Immune Response
11%
Transcriptional Upregulation
11%
Function Cell
11%
Serine/threonine Kinase
11%
Subcellular Localization
11%
Antigen-independent
11%
Kinase Cascade
11%
BMK1
11%
Receptor-mediated
11%
T Cell Response
11%
Composite Element
11%
Genetic Approach
11%
Antigen-specific
11%
Activator protein-1 (AP-1)
11%
Mild Phenotype
11%
Naïve T Cells
11%
T Cell Receptor Signaling
11%
IL-2 Signaling
11%
CD28 Costimulation
11%
IL-2 Production
11%
TSAd
11%
Therapeutic Inhibitors
11%
Apoptosis
11%
Costimulatory Signal
11%
Immunology and Microbiology
CD28
100%
T Cell Receptor
61%
T Cell Activation
53%
Interleukin 2
38%
T Cell
38%
phosphorylation
15%
Promoter Region
15%
Upregulation
15%
Serine
15%
Autoimmune Disease
15%
Cellular Distribution
7%
Naive T Cell
7%
Antigen Specificity
7%
Immune Response
7%
Antigen
7%
Threonine
7%
Programmed Cell Death
7%
Phosphotransferase
7%
Kinase
7%