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Keyphrases
Progranulin
100%
TAR DNA-binding Protein 43 (TDP-43)
100%
Cell Death
100%
Ubiquitin
61%
Positive Inclusion
61%
Frontotemporal Dementia
60%
Chromosome 17q21
50%
Neurodegeneration
40%
Amyotrophic Lateral Sclerosis
40%
Frontotemporal Lobar Degeneration
40%
Motor Neuron Degeneration
21%
Tau Gene
21%
Null mutation
20%
Gene Encoding
20%
TARDBP Gene
20%
TARDBP
20%
Intranuclear
14%
Tau mutation
14%
Neuronal Inclusions
14%
Neurofibrillary Pathology
14%
FTDP-17
14%
Chromosome 17
14%
Progranulin mutation
10%
Promote Apoptosis
10%
C/EBP Homologous Protein
10%
Neuronal Survival
10%
Growth Factors
10%
Knockdown
10%
Endoplasmic Reticulum Stress (ER stress)
10%
Inclusion Formation
10%
Nuclear Proteins
10%
Exon Splicing
10%
Translocation Formation
10%
Transcription Factor
10%
Neurodegenerative Diseases
10%
Pathologic
10%
Cytosol
10%
Disease Mechanisms
10%
Mechanistic Insights
10%
Caspase
10%
Signaling Pathway
10%
Enhanced Sensitivity
10%
Major Protein
10%
Pathological Subtype
10%
Cell Death Pathways
10%
Missense mutation
10%
Cell Culture Model
10%
Duplication
7%
Neuropil
7%
Motor Neuron
7%
Dementia Family
7%
Ubiqutin
7%
Behavior Change
7%
Chromosome 9
7%
Genotype-phenotype Association
7%
Chromosome 3
7%
Cognitive Decline
7%
Autosomal Dominant
7%
Pathogenic Mechanism
7%
Heterogeneous Conditions
7%
Gene mutation
7%
Atrophy
7%
Etiology
7%
Glial Cells
7%
Genetic Linkage Study
7%
Genetic Causes
7%
Temporal Lobe
7%
Dementia with
7%
Relationship Mechanism
7%
Cortex
7%
Frontal Lobe
7%
Microscopic Pathology
7%
Pedigree
7%
Neuroscience
Progranulin
100%
Cell Death
100%
TAR DNA Binding Protein
100%
Ubiquitin
61%
Frontotemporal Dementia
60%
Genetics
50%
Chromosome
50%
Amyotrophic Lateral Sclerosis
40%
Neurodegeneration
40%
Motor Neuron
28%
Nerve Cell Degeneration
21%
Chromosome 17
14%
Neurofibrillary Pathology
14%
Caspase
10%
Missense Mutation
10%
Nuclear Protein
10%
Exon
10%
Programmed Cell Death
10%
Cell Signaling
10%
Cell Culture
10%
Nucleus
10%
Endoplasmic Reticulum Stress
10%
Growth Factor
10%
Ccaat-Enhancer-Binding Proteins
10%
Neurodegenerative Disorder
10%
Neuropil
7%
Chromosome 3
7%
Chromosome 9
7%
Gene Mutation
7%
Microglia
7%
Intron
7%
Temporal Lobe
7%
Cognitive Decline
7%
Frontal Lobe
7%
Biochemistry, Genetics and Molecular Biology
Cell Death
100%
TAR DNA Binding Protein
100%
Ubiquitin
52%
Tau
50%
Chromosome
50%
Genetics
50%
TARDBP
40%
Motor Neuron
16%
Nerve Cell Degeneration
12%
Nuclear Protein
10%
Caspase
10%
Cell Culture
10%
Exon
10%
Missense Mutation
10%
Ccaat-Enhancer-Binding Proteins
10%
Programmed Cell Death
10%
Growth Factor
10%
Endoplasmic Reticulum Stress
10%
Signal Transduction
10%
Chromosome 17
8%