Y.s. Prakash

2024

Estrogen receptors differentially modifies lamellipodial and focal adhesion dynamics in airway smooth muscle cell migration

Ambhore, N. S., Balraj, P., Pabelick, C. M., Prakash, Y. S. & Sathish, V., Jan 1 2024, In: Molecular and Cellular Endocrinology. 579, 112087.

Research output: Contribution to journal › Article › peer-review

2023

Age-associated differences in the human lung extracellular matrix

Ngassie, M. L. K., De Vries, M., Borghuis, T., Timens, W., Sin, D. D., Nickle, D., Joubert, P., Horvatovich, P., Marko-Varga, G., Teske, J. J., Vonk, J. M., Gosens, R., Prakash, Y. S., Burgess, J. K. & Brandsma, C. A., Jun 2023, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 324, 5, p. L799-L814

Research output: Contribution to journal › Article › peer-review

Asthmatic lung fibroblasts promote type 2 immune responses via endoplasmic reticulum stress response dependent thymic stromal lymphopoietin secretion

Drake, L. Y., Koloko Ngassie, M. L., Roos, B. B., Teske, J. J. & Prakash, Y. S., Jan 25 2023, In: Frontiers in Physiology. 14, 1064822.

Research output: Contribution to journal › Article › peer-review

Open Access

Functional a7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics

Khalfaoui, L., Mukhtasimova, N., Kelley, B., Wells, N., Teske, J. J., Roos, B. B., Borkar, N. A., Zhang, E. Y., Sine, S. M., Prakash, Y. S. & Pabelick, C. M., Jul 2023, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 325, 1, p. L17-L29

Research output: Contribution to journal › Article › peer-review

Mechanosensitive Channels in Lung Health and Disease

Migulina, N., Kelley, B., Zhang, E. Y., Pabelick, C. M., Prakash, Y. S. & Vogel, E. R., Sep 28 2023, In: Comprehensive Physiology. 13, 4, p. 5157-5178 22 p.

Research output: Contribution to journal › Article › peer-review

Oxygen and mechanical stretch in the developing lung: risk factors for neonatal and pediatric lung disease

Zhang, E. Y., Bartman, C. M., Prakash, Y. S., Pabelick, C. M. & Vogel, E. R., 2023, In: Frontiers in Medicine. 10, 1214108.

Research output: Contribution to journal › Review article › peer-review

Open Access

2022

Calcium-sensing receptor and CPAP-induced neonatal airway hyperreactivity in mice

Mayer, C. A., Roos, B., Teske, J., Wells, N., Martin, R. J., Chang, W., Pabelick, C. M., Prakash, Y. S. & MacFarlane, P. M., May 2022, In: Pediatric Research. 91, 6, p. 1391-1398 8 p.

Research output: Contribution to journal › Article › peer-review

Cellular Senescence in Aging Lungs and Diseases

Aghali, A., Ngassie, M. L. K., Pabelick, C. M. & Prakash, Y. S., Jun 1 2022, In: Cells. 11, 11, 1781.

Research output: Contribution to journal › Review article › peer-review

Open Access

Cellular senescence is increased in airway smooth muscle cells of elderly persons with asthma

Aghali, A., Khalfaoui, L., Lagnado, A. B., Drake, L. Y., Teske, J. J., Pabelick, C. M., Passos, J. F. & Prakash, Y. S., Nov 1 2022, In: American journal of physiology. Lung cellular and molecular physiology. 323, 5, p. L558-L568

Research output: Contribution to journal › Article › peer-review

CPAP-induced airway hyper-reactivity in mice is modulated by hyaluronan synthase-3

Mayer, C. A., Ganguly, A., Mayer, A., Pabelick, C. M., Prakash, Y. S., Hascall, V. C., Midura, R. J., Cali, V., Flask, C. A., Erokwu, B. O., Martin, R. J. & MacFarlane, P. M., Sep 2022, In: Pediatric Research. 92, 3, p. 685-693 9 p.

Research output: Contribution to journal › Article › peer-review

Hormonal Effects on Asthma, Rhinitis, and Eczema

Weare-Regales, N., Chiarella, S. E., Cardet, J. C., Prakash, Y. S. & Lockey, R. F., Aug 2022, In: Journal of Allergy and Clinical Immunology: In Practice. 10, 8, p. 2066-2073 8 p.

Research output: Contribution to journal › Article › peer-review

Kisspeptins inhibit human airway smooth muscle proliferation

Borkar, N. A., Ambhore, N. S., Kalidhindi, R. S. R., Pabelick, C. M., Prakash, Y. S. & Sathish, V., May 23 2022, In: JCI Insight. 7, 10, e152762.

Research output: Contribution to journal › Article › peer-review

Open Access

Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle

Jackson, D., Walum, J., Banerjee, P., Lewis, B. W., Prakash, Y. S., Sathish, V., Xu, Z. & Britt, R. D., Dec 2022, In: Respiratory Research. 23, 1, 126.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Aging increases senescence, calcium signaling, and extracellular matrix deposition in human airway smooth muscle

Wicher, S. A., Roos, B. B., Teske, J. J., Fang, Y. H., Pabelick, C. & Prakash, Y. S., Jul 2021, In: PloS one. 16, 7 July, e0254710.

Research output: Contribution to journal › Article › peer-review

Open Access

Announcing the editorial board fellowship program of the American Journal of Physiology-lung cellular and molecular physiology

Shimoda, L. A., Bai, C., Bartlett, N. W., Bastarache, J. A., Feghali-Bostwick, C., Kuebler, W. M., Prakash, Y. S., Schmidt, E. P. & Morty, R. E., Jul 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 321, 1, p. L116-L118

Research output: Contribution to journal › Editorial › peer-review

Calcium-Sensing Receptor Contributes to Hyperoxia Effects on Human Fetal Airway Smooth Muscle

Roesler, A. M., Ravix, J., Bartman, C. M., Patel, B. S., Schiliro, M., Roos, B., Nesbitt, L., Pabelick, C. M., Martin, R. J., MacFarlane, P. M. & Prakash, Y. S., Mar 15 2021, In: Frontiers in Physiology. 12, 585895.

Research output: Contribution to journal › Article › peer-review

Open Access

Cellular clocks in hyperoxia effects on [Ca^{2 þ} ]_i regulation in developing human airway smooth muscle

Bartman, C. M., Matveyenko, A., Pabelick, C. & Prakash, Y. S., Mar 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 320, 3, p. L451-L466

Research output: Contribution to journal › Article › peer-review

CPAP protects against hyperoxia-induced increase in airway reactivity in neonatal mice

MacFarlane, P. M., Mayer, C. A., Jafri, A., Pabelick, C. M., Prakash, Y. S. & Martin, R. J., Jul 2021, In: Pediatric Research. 90, 1, p. 52-57 6 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Effects of Hypoxia on Airway, Alveolar Function, and Respiration

Prakash, Y. S., Pabelick, C. M. & MacFarlane, P. M., Jan 1 2021, Hypoxic Respiratory Failure in the Newborn: From Origins to Clinical Management. CRC Press, p. 142-147 6 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic β cell function in type 2 diabetes

Brown, M. R., Holmes, H., Rakshit, K., Javeed, N., Her, T. K., Stiller, A. A., Sen, S., Shull, G. E., Prakash, Y. S., Romero, M. F. & Matveyenko, A. V., Sep 1 2021, In: Journal of Clinical Investigation. 131, 17, e142365.

Research output: Contribution to journal › Article › peer-review

Open Access

Glial-derived neurotrophic factor in human airway smooth muscle

Bhallamudi, S., Roos, B. B., Teske, J. J., Wicher, S. A., McConico, A., M. Pabelick, C., Sathish, V. & Prakash, Y. S., Dec 2021, In: Journal of Cellular Physiology. 236, 12, p. 8184-8196 13 p.

Research output: Contribution to journal › Article › peer-review

Intermittent hypoxia-hyperoxia and oxidative stress in developing human airway smooth muscle

Bartman, C. M., Awari, D. W., Pabelick, C. M. & Prakash, Y. S., Sep 2021, In: Antioxidants. 10, 9, 1400.

Research output: Contribution to journal › Article › peer-review

Open Access

Network and co-expression analysis of airway smooth muscle cell transcriptome delineates potential gene signatures in asthma

Banerjee, P., Balraj, P., Ambhore, N. S., Wicher, S. A., Britt, R. D., Pabelick, C. M., Prakash, Y. S. & Sathish, V., Dec 2021, In: Scientific reports. 11, 1, 14386.

Research output: Contribution to journal › Article › peer-review

Open Access

Neurotrophin Regulation and Signaling in Airway Smooth Muscle

Roos, B. B., Teske, J. J., Bhallamudi, S., Pabelick, C. M., Sathish, V. & Prakash, Y. S., 2021, Advances in Experimental Medicine and Biology. Springer, p. 109-121 13 p. (Advances in Experimental Medicine and Biology; vol. 1304).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Nicotinic α7 acetylcholine receptor (α7nAChR) in human airway smooth muscle

Borkar, N. A., Roos, B., Prakash, Y. S., Sathish, V. & Pabelick, C. M., Jul 30 2021, In: Archives of Biochemistry and Biophysics. 706, 108897.

Research output: Contribution to journal › Article › peer-review

Open Access

Passive siRNA transfection method for gene knockdown in air-liquid interface airway epithelial cell cultures

Bartman, C. M., Stelzig, K. E., Linden, D. R., Prakash, Y. S. & Chiarella, S. E., Jul 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 321, 1, p. L280-L286

Research output: Contribution to journal › Article › peer-review

Prenatal maternal lipopolysaccharide and mild newborn hyperoxia increase intrapulmonary airway but not vessel reactivity in a mouse model

Kuper-Sassé, M. E., Macfarlane, P. M., Mayer, C. A., Martin, R. J., Prakash, Y. S., Pabelick, C. M. & Raffay, T. M., Mar 2021, In: Children. 8, 3, 195.

Research output: Contribution to journal › Article › peer-review

Open Access

Senolytics reduce coronavirus-related mortality in old mice

Camell, C. D., Yousefzadeh, M. J., Zhu, Y., Langhi Prata, L. G. P., Huggins, M. A., Pierson, M., Zhang, L., O’Kelly, R. D., Pirtskhalava, T., Xun, P., Ejima, K., Xue, A., Tripathi, U., Espindola-Netto, J. M., Giorgadze, N., Atkinson, E. J., Inman, C. L., Johnson, K. O., Cholensky, S. H., Carlson, T. W., & 14 othersLeBrasseur, N. K., Khosla, S., Gerard O’Sullivan, M., Allison, D. B., Jameson, S. C., Meves, A., Li, M., Prakash, Y. S., Chiarella, S. E., Hamilton, S. E., Tchkonia, T., Niedernhofer, L. J., Kirkland, J. L. & Robbins, P. D., Jul 16 2021, In: Science. 373, 6552, eabe4832.

Research output: Contribution to journal › Article › peer-review

Open Access

Sex, Cells, and Asthma

Chiarella, S. E., Cardet, J. C. & Prakash, Y. S., Jul 2021, In: Mayo Clinic proceedings. 96, 7, p. 1955-1969 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

The stress of lung aging: Endoplasmic reticulum and senescence tête-à-tête

Ngassie, M. L. K., Brandsma, C. A., Gosens, R., Prakash, Y. S. & Burgess, J. K., 2021, In: Physiology. 36, 3, p. 150-159 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2020

Asthma without borders

Prakash, Y. S., May 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 5, p. L1001-L1003

Research output: Contribution to journal › Editorial › peer-review

Open Access

2 Scopus citations

Bringing the cellular clock into understanding lung disease: it’s time, period!

Bartman, C. M. & Prakash, Y. S., Aug 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 319, 2, p. L273-L276

Research output: Contribution to journal › Editorial › peer-review

Cholinergic neuroplasticity in asthma driven by TrkB signaling

Dragunas, G., Woest, M. E., Nijboer, S., Bos, S. T., van Asselt, J., de Groot, A. P., Vohlídalová, E., Vermeulen, C. J., Ditz, B., Vonk, J. M., Koppelman, G. H., van den Berge, M., ten Hacken, N. H. T., Timens, W., Munhoz, C. D., Prakash, Y. S., Gosens, R. & Kistemaker, L. E. M., Jun 1 2020, In: FASEB Journal. 34, 6, p. 7703-7717 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Class C GPCRs in the airway

Patel, B. S., Ravix, J., Pabelick, C. & Prakash, Y. S., Apr 2020, In: Current Opinion in Pharmacology. 51, p. 19-28 10 p.

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Contributions of IL-33 in Non-hematopoietic Lung Cells to Obstructive Lung Disease

Drake, L. Y. & Prakash, Y. S., Aug 13 2020, In: Frontiers in immunology. 11, 1798.

Research output: Contribution to journal › Review article › peer-review

Open Access

Erratum: The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8⁺ T Cell Fitness and Functionality (Immunity (2019) 51(3) (491–507.e7), (S1074761319303644), (10.1016/j.immuni.2019.08.013))

Li, C., Zhu, B., Son, Y. M., Wang, Z., Jiang, L., Xiang, M., Ye, Z., Beckermann, K. E., Wu, Y., Jenkins, J. W., Siska, P. J., Vincent, B. G., Prakash, Y. S., Peikert, T., Edelson, B. T., Taneja, R., Kaplan, M. H., Rathmell, J. C., Dong, H., Hitosugi, T., & 1 othersSun, J., Jan 14 2020, In: Immunity. 52, 1, p. 201-202 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Estrogen receptors differentially regulate intracellular calcium handling in human nonasthmatic and asthmatic airway smooth muscle cells

Bhallamudi, S., Connell, J., Pabelick, C. M., Prakash, Y. S. & Sathish, V., 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 1, p. L112-L124

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Estrogen regulates the expression of SARS-CoV-2 receptor ACE2 in differentiated airway epithelial cells

Stelzig, K. E., Canepa-Escaro, F., Schiliro, M., Berdnikovs, S., Prakash, Y. S. & Chiarella, S. E., Jun 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 6

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Hydrogen sulfide, oxygen, and calcium regulation in developing human airway smooth muscle

Bartman, C. M., Schiliro, M., Helan, M., Prakash, Y. S., Linden, D. & Pabelick, C., Sep 1 2020, In: FASEB Journal. 34, 9, p. 12991-13004 14 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

It's about time: Clocks in the developing lung

Bartman, C. M., Matveyenko, A. & Prakash, Y. S., Jan 2 2020, In: Journal of Clinical Investigation. 130, 1, p. 39-50 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Noncanonical role for Ku70/80 in the prevention of allergic airway inflammation via maintenance of airway epithelial cell organelle homeostasis

Rehman, R., Vijayakumar, V. E., Jaiswal, A., Jain, X. V., Mukherjee, S., Vellarikkal, X. S. K., Dieffenbach, P. B., Fredenburgh, L. E., Prakash, X. Y. S., Ghosh, B., Agrawal, A. & Mabalirajan, U., Oct 6 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 319, 4, p. L728-L741

Research output: Contribution to journal › Article › peer-review

Sex steroids skew ACE2 expression in human airway: A contributing factor to sex differences in COVID-19?

Kalidhindi, R. S. R., Borkar, N. A., Ambhore, N. S., Pabelick, C. M., Prakash, Y. S. & Sathish, V., Nov 3 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 319, 5, p. L843-L847

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Upregulation of airway smooth muscle calcium-sensing receptor by lowmolecular- weight hyaluronan

Lazrak, A., Yu, Z., Doran, S., Jian, M. Y., Creighton, J., Laube, M., Garantziotis, S., Prakash, Y. S. & Matalon, S., 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 3, p. L459-L471

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

YAP/TAZ are Activated by Mechanical and Hormonal Stimuli in Myometrium and Exhibit Increased Baseline Activation in Uterine Fibroids

Purdy, M. K. P., Ducharme, M., Haak, A. J., Ravix, J., Tan, Q., Sicard, D., Prakash, Y. S., Tschumperlin, D. J. & Stewart, E. A., Apr 1 2020, In: Reproductive Sciences. 27, 4, p. 1074-1085 12 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2019

Airway Innervation and Plasticity in Asthma

Kistemaker, L. E. M. & Prakash, Y. S., Jul 2019, In: Physiology. 34, 4, p. 283-298 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

15 Scopus citations

Androgen receptor-mediated regulation of intracellular calcium in human airway smooth muscle cells

Kalidhindi, R. S. R., Katragadda, R., Beauchamp, K. L., Pabelick, C. M., Prakash, Y. S. & Sathish, V., 2019, In: Cellular Physiology and Biochemistry. 53, 1, p. 215-228 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Calcium sensing receptor in developing human airway smooth muscle

Roesler, A. M., Wicher, S. A., Ravix, J., Britt, R. D., Manlove, L., Teske, J. J., Cummings, K., Thompson, M. A., Farver, C., MacFarlane, P., Pabelick, C. M. & Prakash, Y. S., Aug 2019, In: Journal of Cellular Physiology. 234, 8, p. 14187-14197 11 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Caveolae, caveolin-1 and lung diseases of aging

Wicher, S. A., Prakash, Y. S. & Pabelick, C. M., Mar 4 2019, In: Expert Review of Respiratory Medicine. 13, 3, p. 291-300 10 p.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Caveolin-1 scaffolding domain peptide prevents hyperoxia-induced airway remodeling in a neonatal mouse model

Vogel, E. R., Manlove, L. J., Kuipers, I., Thompson, M. A., Fang, Y. H., Freeman, M. R., Britt, R. D., Faksh, A., Yang, B., Prakash, Y. S. & Pabelick, C. M., 2019, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 1, p. L99-L108

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis

Ligresti, G., Caporarello, N., Meridew, J. A., Jones, D. L., Tan, Q., Choi, K. M., Haak, A. J., Aravamudhan, A., Roden, A. C., Prakash, Y. S., Lomberk, G., Urrutia, R. A. & Tschumperlin, D. J., 2019, In: JCI Insight. 4, 12, e127111.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Y.s. Prakash, MD, PhD

Research output

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