Projects per year
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Molecular mechanisms of PINK1-PRKN directed mitochondrial quality control
National Institute of Neurological Disorders and Stroke
9/1/19 → 5/31/24
Project: Research project
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Mitochondrial Sirtuin 3 in Parkinson's disease
Mclean, P. P. J., Springer, W. & McLean, P. J.
National Institute of Neurological Disorders and Stroke
6/1/19 → 5/31/24
Project: Research project
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Selective autophagy in Alzheimer's disease and related dementias
Springer, W. & Fryer, J. D.
8/1/19 → 7/31/21
Project: Research project
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Early-Onset Parkinson's Disease Is a Mitochondrial Disease: A Nigral Mitochondrial Cytopathy
Congressionally Directed Medical Research Programs
8/15/17 → 8/14/20
Project: Research project
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Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent
Hou, X., Chen, T. H. Y., Koga, S., Bredenberg, J. M., Faroqi, A. H., Delenclos, M., Bu, G., Wszolek, Z. K., Carr, J. A., Ross, O. A., McLean, P. J., Murray, M. E., Dickson, D. W., Fiesel, F. C. & Springer, W., Sep 2023, In: Brain Pathology. 33, 5, e13175.Research output: Contribution to journal › Article › peer-review
Open Access -
Interplay of Impaired Cellular Bioenergetics and Autophagy in PMM2-CDG
Ligezka, A. N., Budhraja, R., Nishiyama, Y., Fiesel, F. C., Preston, G., Edmondson, A., Ranatunga, W., Van Hove, J. L. K., Watzlawik, J. O., Springer, W., Pandey, A., Morava, E. & Kozicz, T., Aug 2023, In: Genes. 14, 8, 1585.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure-based design and characterization of Parkin-activating mutations
Stevens, M. U., Croteau, N., Eldeeb, M. A., Antico, O., Zeng, Z. W., Toth, R., Durcan, T. M., Springer, W., Fon, E. A., Muqit, M. M. K. & Trempe, J. F., 2023, In: Life Science Alliance. 6, 6, e202201419.Research output: Contribution to journal › Article › peer-review
Open Access -
Substitution of PINK1 Gly411 modulates substrate receptivity and turnover
Fiesel, F. C., Fričová, D., Hayes, C. S., Coban, M. A., Hudec, R., Bredenberg, J. M., Broadway, B. J., Markham, B. N., Yan, T., Boneski, P. K., Fiorino, G., Watzlawik, J. O., Hou, X., McCarty, A. M., Lewis-Tuffin, L. J., Zhong, J., Madden, B. J., Ordureau, A., An, H., Puschmann, A., & 5 others , 2023, In: Autophagy. 19, 6, p. 1711-1732 22 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cathepsin B p.Gly284Val Variant in Parkinson’s Disease Pathogenesis
Milanowski, L. M., Hou, X., Bredenberg, J. M., Fiesel, F. C., Cocker, L. T., Soto-Beasley, A. I., Walton, R. L., Strongosky, A. J., Faroqi, A. H., Barcikowska, M., Boczarska-Jedynak, M., Dulski, J., Fedoryshyn, L., Janik, P., Potulska-Chromik, A., Karpinsky, K., Krygowska-Wajs, A., Lynch, T., Olszewska, D. A., Opala, G., & 18 others , Jul 1 2022, In: International journal of molecular sciences. 23, 13, 7086.Research output: Contribution to journal › Article › peer-review
Open Access