Projects per year
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Dive into the research topics where Seiko Ikezu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 2 Active
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Tumor susceptibility gene 101, a new microglial therapy candidate for Alzheimer’s disease to prevent cognitive decline
9/1/23 → 8/31/26
Project: Research project
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Therapeutic evaluation of targeting Tau Tubulin kinase-1 in Alzheimer’s disease
2/1/23 → 1/31/24
Project: Research project
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Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice
Yukawa, K., Yamamoto-Mcguire, S., Cafaro, L., Hong, C., Kamme, F., Ikezu, T. & Ikezu, S., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 166.Research output: Contribution to journal › Article › peer-review
Open Access -
Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications
Zhang, Z., Yu, K., You, Y., Jiang, P., Wu, Z., DeTure, M. A., Dickson, D. W., Ikezu, S., Peng, J. & Ikezu, T., Aug 2023, In: Journal of Extracellular Vesicles. 12, 8, 12358.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
Yin, Z., Herron, S., Silveira, S., Kleemann, K., Gauthier, C., Mallah, D., Cheng, Y., Margeta, M. A., Pitts, K. M., Barry, J. L., Subramanian, A., Shorey, H., Brandao, W., Durao, A., Delpech, J. C., Madore, C., Jedrychowski, M., Ajay, A. K., Murugaiyan, G., Hersh, S. W., & 3 others, Jul 2023, In: Nature Neuroscience. 26, 7, p. 1196-1207 12 p.Research output: Contribution to journal › Article › peer-review
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Microglial WNT5A supports dendritic spines maturation and neuronal firing
Yeh, H., Woodbury, M. E., Ingraham Dixie, K. L., Ikezu, T. & Ikezu, S., Jan 2023, In: Brain, Behavior, and Immunity. 107, p. 403-413 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Alzheimer’s disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells
You, Y., Hersh, S. W., Aslebagh, R., Shaffer, S. A., Ikezu, S., Mez, J., Lunetta, K. L., Logue, M. W., Farrer, L. A. & Ikezu, T., Jun 2022, In: Aging Cell. 21, 6, e13617.Research output: Contribution to journal › Article › peer-review
Open Access