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Dive into the research topics where Ruth Lupu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 8 Finished
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Fatty Acid Synthase:Molecular Target for Breast Cancer Therapy & Chemoprevention
Lupu, R. (CoPI) & Lupu, R. (PI)
9/16/05 → 6/30/17
Project: Research project
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Identification of the Her-2 Functional Site: Blockage of Receptor Heterodimerization
Lupu, R. (PI)
1/1/05 → 12/31/05
Project: Research project
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Interaction between Cyr61 and avbeta3 in Breast Cancer: Role in Taxane Resistance
Lupu, R. (PI)
1/1/05 → 12/31/05
Project: Research project
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HEREGULIN (GP30) EXPRESSION AND DRUG RESISTANCE
Lupu, R. (PI) & Lupu, R. R. (CoPI)
6/1/95 → 1/31/98
Project: Research project
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Fatty acid synthase (FASN) inhibition cooperates with BH3 mimetic drugs to overcome resistance to mitochondrial apoptosis in pancreatic cancer
Steen, T. V., Espinoza, I., Duran, C., Casadevall, G., Serrano-Hervás, E., Cuyàs, E., Verdura, S., Kemble, G., Kaufmann, S. H., McWilliams, R., Osuna, S., Billadeau, D. D., Menendez, J. A. & Lupu, R., Apr 2025, In: Neoplasia (United States). 62, 101143.Research output: Contribution to journal › Article › peer-review
Open Access -
Metabolic hallmarks of trastuzumab resistance
Martin-Castillo, B., Verdura, S., Llop-Hernández, À., Lupu, R., Cuyàs, E. & Menendez, J. A., 2025, In: Expert opinion on therapeutic targets. 29, 7, p. 457-479 23 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Mitochondrial priming and response to BH3 mimetics in “one-two punch” senogenic-senolytic strategies
López, J., Llop-Hernández, À., Verdura, S., Serrano-Hervás, E., Martinez-Balibrea, E., Bosch-Barrera, J., Teixidor, E., López-Bonet, E., Martin-Castillo, B., Sardanyés, J., Alarcón, T., Lupu, R., Cuyàs, E. & Menendez, J. A., Dec 2025, In: Cell Death Discovery. 11, 1, 91.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial priming in therapy-induced senescence: implications for CAR-T/NK immunosenolytic therapy
Menendez, J. A., Lupu, R., Martin-Castillo, B., Sardanyés, J., Alarcón, T., Verdura, S. & Cuyàs, E., 2025, In: Frontiers in immunology. 16, 1695244.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity
Cuyàs, E., Pedarra, S., Verdura, S., Pardo, M. A., Espin Garcia, R., Serrano-Hervás, E., Llop-Hernández, À., Teixidor, E., Bosch-Barrera, J., López-Bonet, E., Martin-Castillo, B., Lupu, R., Pujana, M. A., Sardanyès, J., Alarcón, T. & Menendez, J. A., Dec 2024, In: Cell Death Discovery. 10, 1, 417.Research output: Contribution to journal › Article › peer-review
Open Access